CD44v6‐peptide functionalized nanoparticles selectively bind to metastatic cancer cells

CD44v6 peptide functionalized nanoparticles are fabricated in a facile and controllable way to selectively bind to CD44v6 positive tumor cells with highly efficient anticancer and antimetastatic properties. The reported modular synthesis and facile preparation makes this system highly potent for dev...

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Hauptverfasser: Li, Linxian (VerfasserIn) , Levkin, Pavel (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2017
In: Advanced science
Year: 2016, Jahrgang: 4, Heft: 1
ISSN:2198-3844
DOI:10.1002/advs.201600202
Online-Zugang:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1002/advs.201600202
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.201600202
Volltext
Verfasserangaben:Linxian Li, Mark Schmitt, Alexandra Matzke‐Ogi, Parvesh Wadhwani, Veronique Orian‐Rousseau, and Pavel A. Levkin
Beschreibung
Zusammenfassung:CD44v6 peptide functionalized nanoparticles are fabricated in a facile and controllable way to selectively bind to CD44v6 positive tumor cells with highly efficient anticancer and antimetastatic properties. The reported modular synthesis and facile preparation makes this system highly potent for developing novel multifunctional nanocarriers for therapeutic and/or diagnostic anticancer applications.
Beschreibung:First published: 20 December 2016
Gesehen am 13.09.2018
Beschreibung:Online Resource
ISSN:2198-3844
DOI:10.1002/advs.201600202