Non-coding RNA in hepatocellular carcinoma: mechanisms, biomarkers and therapeutic targets

The majority of the human genome is not translated into proteins but can be transcribed into RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins, they contribute to diseases such as cancer. Here, we review examples of the functions of ncRNAs in liver cancer and their p...

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Hauptverfasser: Klingenberg, Marcel (VerfasserIn) , Diederichs, Sven (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2017 Apr 22
In: Journal of hepatology
Year: 2017, Jahrgang: 67, Heft: 3, Pages: 603-618
ISSN:1600-0641
DOI:10.1016/j.jhep.2017.04.009
Online-Zugang:Verlag, Volltext: https://doi.org/10.1016/j.jhep.2017.04.009
Verlag, Volltext: https://www.journal-of-hepatology.eu/article/S0168-8278(17)30250-7/abstract
Volltext
Verfasserangaben:Marcel Klingenberg, Akiko Matsuda, Sven Diederichs, Tushar Patel
Beschreibung
Zusammenfassung:The majority of the human genome is not translated into proteins but can be transcribed into RNA. Even though the resulting non-coding RNAs (ncRNAs) do not encode for proteins, they contribute to diseases such as cancer. Here, we review examples of the functions of ncRNAs in liver cancer and their potential use for the detection and treatment of liver cancer.
Beschreibung:Gesehen am 14.09.2018
Beschreibung:Online Resource
ISSN:1600-0641
DOI:10.1016/j.jhep.2017.04.009