Clinical feasibility study for detection of myocardial oedema by a cine SSFP sequence in comparison to a conventional T2-weighted sequence
Background: Cardiovascular magnetic resonance (CMR) T2-imaging is oedema-sensitive and can detect increased myocardial water content to potentially distinguish acute from chronic myocardial infarction (AMI/CMI). Currently applied conventional black-blood T2-weighted-turbo-spin-echo (T2-BB-TSE)-seque...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2012
|
| In: |
Clinical research in cardiology
Year: 2011, Jahrgang: 101, Heft: 2, Pages: 125-131 |
| ISSN: | 1861-0692 |
| DOI: | 10.1007/s00392-011-0373-5 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1007/s00392-011-0373-5 Verlag, Volltext: https://doi.org/10.1007/s00392-011-0373-5 
|
| Verfasserangaben: | Henning Steen, Frederik Voss, Florian André, Mirja Neizel, Tim Schäufele, Stephanie Lehrke, Dirk Lossnitzer, Evangelos Giannitsis, Hugo A. Katus |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1581137591 | ||
| 003 | DE-627 | ||
| 005 | 20220815014031.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180920r20122011xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00392-011-0373-5 |2 doi | |
| 035 | |a (DE-627)1581137591 | ||
| 035 | |a (DE-576)511137591 | ||
| 035 | |a (DE-599)BSZ511137591 | ||
| 035 | |a (OCoLC)1341018757 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Steen, Henning |d 1972- |e VerfasserIn |0 (DE-588)123681669 |0 (DE-627)706393600 |0 (DE-576)293824851 |4 aut | |
| 245 | 1 | 0 | |a Clinical feasibility study for detection of myocardial oedema by a cine SSFP sequence in comparison to a conventional T2-weighted sequence |c Henning Steen, Frederik Voss, Florian André, Mirja Neizel, Tim Schäufele, Stephanie Lehrke, Dirk Lossnitzer, Evangelos Giannitsis, Hugo A. Katus |
| 264 | 1 | |c 2012 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a First Online: 30 October 2011 | ||
| 500 | |a Gesehen am 20.09.2018 | ||
| 520 | |a Background: Cardiovascular magnetic resonance (CMR) T2-imaging is oedema-sensitive and can detect increased myocardial water content to potentially distinguish acute from chronic myocardial infarction (AMI/CMI). Currently applied conventional black-blood T2-weighted-turbo-spin-echo (T2-BB-TSE)-sequences cause various artefacts which limit their image quality and possibly hamper their interpretation. Image contrast of conventional cine steady-state free precession (SSFP)-sequences partly consists of T2 oedema-sensitive information. We therefore sought to prospectively evaluate SSFP cine-imaging to detect myocardial oedema and differentiate AMI from CMI. Methods: We examined 60 patients with AMI, 30 patients with CMI and 30 healthy volunteers using a 1.5 Tesla-MR whole body scanner. In a blinded fashion, myocardial oedema was assessed with T2-BB-TSE and SSFP-sequences, late gadolinium contrast-enhanced (LGE) CMR images being deemed as the standard reference for identification of infarcted myocardium. Assessment of presence of CMR detectable myocardial oedema was performed visually and quantitatively. P < 0.05 was considered statistically significant.ResultsThe contrast-to-noise ratio (CNR) in AMI patients was significantly higher (SSFP-STEMI and SSFP-NSTEMI: 19 ± 12 and 20 ± 14; T2-BB-TSE STEMI and T2-BB-TSE-NSTEMI: 33 ± 16 and 31 ± 13) than in CMI for both MR-sequences (SSFP-STEMI and NSTEMI: 3.5 ± 1.5 and T2-BB-TSE:9.3 ± 9.6, p for all <0.001). By visual analysis, SSFP images achieved a sensitivity of 96%, a specificity of 87%, positive and negative predictive values of 95 and 92% when compared to the existence of gadolinium contrast-enhanced scar imaging. Similarly, for T2-BB-TSE, sensitivity and specificity were 93 and 83% with positive and negative predictive values of 92 and 90%. Inter-observer variability was 0.90 for SSFP and 0.83 for T2-BB-TSE images. Conclusion: A standard clinical SSFP sequence is not inferior to T2-BB-TSE for the detection of myocardial oedema and can be used to reliably distinguish AMI from CMI. Especially in patients with insufficient T2-BB-TSE image quality, the SSFP sequence may be an alternative for the detection of myocardial oedema. | ||
| 534 | |c 2011 | ||
| 650 | 4 | |a Magnetic resonance imaging | |
| 650 | 4 | |a Myocardial infarction | |
| 650 | 4 | |a Myocardial oedema | |
| 650 | 4 | |a Steady-state free precession sequence | |
| 700 | 1 | |a Voss, Frederik |d 1968- |e VerfasserIn |0 (DE-588)122527364 |0 (DE-627)705940152 |0 (DE-576)293308845 |4 aut | |
| 700 | 1 | |a André, Florian |d 1983- |e VerfasserIn |0 (DE-588)1051060230 |0 (DE-627)785671714 |0 (DE-576)405733267 |4 aut | |
| 700 | 1 | |a Lehrke, Stephanie |d 1976- |e VerfasserIn |0 (DE-588)123769175 |0 (DE-627)706420756 |0 (DE-576)29387008X |4 aut | |
| 700 | 1 | |a Loßnitzer, Dirk |d 1972- |e VerfasserIn |0 (DE-588)124754031 |0 (DE-627)365721506 |0 (DE-576)29448325X |4 aut | |
| 700 | 1 | |a Giannitsis, Evangelos |e VerfasserIn |0 (DE-588)113336241 |0 (DE-627)577184091 |0 (DE-576)289759579 |4 aut | |
| 700 | 1 | |a Katus, Hugo |d 1951- |e VerfasserIn |0 (DE-588)108916618 |0 (DE-627)577155040 |0 (DE-576)289625076 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Clinical research in cardiology |d Berlin : Springer, 2006 |g 101(2012), 2, Seite 125-131 |h Online-Ressource |w (DE-627)506287343 |w (DE-600)2218331-0 |w (DE-576)251097692 |x 1861-0692 |7 nnas |a Clinical feasibility study for detection of myocardial oedema by a cine SSFP sequence in comparison to a conventional T2-weighted sequence |
| 773 | 1 | 8 | |g volume:101 |g year:2012 |g number:2 |g pages:125-131 |g extent:7 |a Clinical feasibility study for detection of myocardial oedema by a cine SSFP sequence in comparison to a conventional T2-weighted sequence |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00392-011-0373-5 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00392-011-0373-5 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180920 | ||
| 993 | |a Article | ||
| 994 | |a 2012 | ||
| 998 | |g 108916618 |a Katus, Hugo |m 108916618:Katus, Hugo |d 910000 |d 910100 |e 910000PK108916618 |e 910100PK108916618 |k 0/910000/ |k 1/910000/910100/ |p 9 |y j | ||
| 998 | |g 113336241 |a Giannitsis, Evangelos |m 113336241:Giannitsis, Evangelos |d 910000 |d 910100 |e 910000PG113336241 |e 910100PG113336241 |k 0/910000/ |k 1/910000/910100/ |p 8 | ||
| 998 | |g 124754031 |a Loßnitzer, Dirk |m 124754031:Loßnitzer, Dirk |d 910000 |d 910100 |e 910000PL124754031 |e 910100PL124754031 |k 0/910000/ |k 1/910000/910100/ |p 7 | ||
| 998 | |g 123769175 |a Lehrke, Stephanie |m 123769175:Lehrke, Stephanie |d 910000 |d 910100 |e 910000PL123769175 |e 910100PL123769175 |k 0/910000/ |k 1/910000/910100/ |p 6 | ||
| 998 | |g 1051060230 |a André, Florian |m 1051060230:André, Florian |d 910000 |d 910100 |e 910000PA1051060230 |e 910100PA1051060230 |k 0/910000/ |k 1/910000/910100/ |p 3 | ||
| 998 | |g 122527364 |a Voss, Frederik |m 122527364:Voss, Frederik |d 910000 |d 910100 |e 910000PV122527364 |e 910100PV122527364 |k 0/910000/ |k 1/910000/910100/ |p 2 | ||
| 998 | |g 123681669 |a Steen, Henning |m 123681669:Steen, Henning |d 50000 |e 50000PS123681669 |k 0/50000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1581137591 |e 3025894520 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"id":{"zdb":["2218331-0"],"eki":["506287343"],"issn":["1861-0692"]},"physDesc":[{"extent":"Online-Ressource"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Clinical feasibility study for detection of myocardial oedema by a cine SSFP sequence in comparison to a conventional T2-weighted sequenceClinical research in cardiology","title":[{"title":"Clinical research in cardiology","title_sort":"Clinical research in cardiology"}],"origin":[{"publisherPlace":"Berlin","dateIssuedKey":"2006","dateIssuedDisp":"2006-","publisher":"Springer"}],"part":{"text":"101(2012), 2, Seite 125-131","pages":"125-131","extent":"7","issue":"2","year":"2012","volume":"101"},"language":["eng"],"pubHistory":["95.2006 -"],"recId":"506287343"}],"origin":[{"dateIssuedKey":"2012","dateIssuedDisp":"2012"}],"title":[{"title_sort":"Clinical feasibility study for detection of myocardial oedema by a cine SSFP sequence in comparison to a conventional T2-weighted sequence","title":"Clinical feasibility study for detection of myocardial oedema by a cine SSFP sequence in comparison to a conventional T2-weighted sequence"}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"doi":["10.1007/s00392-011-0373-5"],"eki":["1581137591"]},"physDesc":[{"extent":"7 S."}],"recId":"1581137591","person":[{"role":"aut","family":"Steen","given":"Henning","display":"Steen, Henning"},{"display":"Voss, Frederik","given":"Frederik","family":"Voss","role":"aut"},{"given":"Florian","display":"André, Florian","role":"aut","family":"André"},{"given":"Stephanie","display":"Lehrke, Stephanie","family":"Lehrke","role":"aut"},{"given":"Dirk","display":"Loßnitzer, Dirk","role":"aut","family":"Loßnitzer"},{"family":"Giannitsis","role":"aut","display":"Giannitsis, Evangelos","given":"Evangelos"},{"given":"Hugo","display":"Katus, Hugo","role":"aut","family":"Katus"}],"note":["First Online: 30 October 2011","Gesehen am 20.09.2018"],"language":["eng"],"name":{"displayForm":["Henning Steen, Frederik Voss, Florian André, Mirja Neizel, Tim Schäufele, Stephanie Lehrke, Dirk Lossnitzer, Evangelos Giannitsis, Hugo A. Katus"]}} | ||
| SRT | |a STEENHENNICLINICALFE2012 | ||