Non-specific effects of childhood vaccinations: a case control study nested into a health and demographic surveillance system in rural Burkina Faso
Introduction previous studies in African countries have been suggestive of non-specific effects (NSE) of vaccination on child survival. Live vaccines (e.g. measles, MV) have been found to reduce child mortality while inactivated vaccines (e.g. diphtheria-tetanus-pertussis, DTP) have been associated...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
15 November 2017
|
| In: |
Vaccine
Year: 2017, Jahrgang: 35, Heft: 51, Pages: 7114-7120 |
| ISSN: | 1873-2518 |
| DOI: | 10.1016/j.vaccine.2017.10.089 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.vaccine.2017.10.089 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0264410X17314974 
|
| Verfasserangaben: | G. Pfeiffer, A.B. Fisker, E. Nebié, J. Hengelbrock, A. Sié, H. Becher, O. Müller |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1581252072 | ||
| 003 | DE-627 | ||
| 005 | 20220815015750.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180924s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.vaccine.2017.10.089 |2 doi | |
| 035 | |a (DE-627)1581252072 | ||
| 035 | |a (DE-576)511252072 | ||
| 035 | |a (DE-599)BSZ511252072 | ||
| 035 | |a (OCoLC)1341018946 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Pfeiffer, Gillian |d 1989- |e VerfasserIn |0 (DE-588)1167738918 |0 (DE-627)103125935X |0 (DE-576)511251319 |4 aut | |
| 245 | 1 | 0 | |a Non-specific effects of childhood vaccinations |b a case control study nested into a health and demographic surveillance system in rural Burkina Faso |c G. Pfeiffer, A.B. Fisker, E. Nebié, J. Hengelbrock, A. Sié, H. Becher, O. Müller |
| 264 | 1 | |c 15 November 2017 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 24.09.2018 | ||
| 520 | |a Introduction previous studies in African countries have been suggestive of non-specific effects (NSE) of vaccination on child survival. Live vaccines (e.g. measles, MV) have been found to reduce child mortality while inactivated vaccines (e.g. diphtheria-tetanus-pertussis, DTP) have been associated with increased mortality; NSE were often found to be sex-specific. Methods a case-control study nested into the Health and Demographic Surveillance System (HDSS) cohort of the Centre de Recherche en Santé de Nouna (CRSN) was conducted in northwestern Burkina Faso. A total of 3,010 children born in 2009-11, were included in the study, 375 cases and 2635 age and village matched controls. The main outcome measures were the mortality odds ratios for vaccinated versus unvaccinated children by antigen. The main outcome measures were the mortality odds ratios for vaccinated versus unvaccinated children by antigen. Results Most deaths occurred in late infancy, and there were significantly more deaths in males as compared to females (OR 1.29, CI 1.04-1.60). Overall, there was no statistically significant association between vaccine status and mortality. However, among children in the age group 2-8 months, there was a consistent sex-differential pattern for all doses of oral polio vaccine combined with pentavalent vaccine (OPV+Penta), with the vaccines being associated with lower mortality in boys, but not in girls. Routine MV+yellow fever vaccine was associated with reduced mortality, but only before mass vaccination campaigns with meningitis and measles vaccines took place. Conclusions: The findings of this study provide further support on the existence of NSE of childhood vaccinations in a large population of rural Burkina Faso. More randomized controlled trials are needed to confirm these observations. | ||
| 650 | 4 | |a Africa | |
| 650 | 4 | |a Case control study | |
| 650 | 4 | |a Childhood vaccination | |
| 650 | 4 | |a Non-specific effects | |
| 700 | 1 | |a Becher, Heiko |e VerfasserIn |0 (DE-588)1027740677 |0 (DE-627)729629260 |0 (DE-576)375063439 |4 aut | |
| 700 | 1 | |a Müller, Olaf |d 1954- |e VerfasserIn |0 (DE-588)143910698 |0 (DE-627)655906479 |0 (DE-576)339649453 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Vaccine |d Amsterdam : Elsevier, 1983 |g 35(2017), 51, Seite 7114-7120 |h Online-Ressource |w (DE-627)266886078 |w (DE-600)1468474-3 |w (DE-576)075961857 |x 1873-2518 |7 nnas |a Non-specific effects of childhood vaccinations a case control study nested into a health and demographic surveillance system in rural Burkina Faso |
| 773 | 1 | 8 | |g volume:35 |g year:2017 |g number:51 |g pages:7114-7120 |g extent:7 |a Non-specific effects of childhood vaccinations a case control study nested into a health and demographic surveillance system in rural Burkina Faso |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.vaccine.2017.10.089 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S0264410X17314974 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180924 | ||
| 993 | |a Article | ||
| 994 | |a 2017 | ||
| 998 | |g 143910698 |a Müller, Olaf |m 143910698:Müller, Olaf |d 910000 |d 912800 |e 910000PM143910698 |e 912800PM143910698 |k 0/910000/ |k 1/910000/912800/ |p 7 |y j | ||
| 998 | |g 1027740677 |a Becher, Heiko |m 1027740677:Becher, Heiko |d 910000 |d 911700 |e 910000PB1027740677 |e 911700PB1027740677 |k 0/910000/ |k 1/910000/911700/ |p 6 | ||
| 998 | |g 1167738918 |a Pfeiffer, Gillian |m 1167738918:Pfeiffer, Gillian |d 910000 |d 912800 |e 910000PP1167738918 |e 912800PP1167738918 |k 0/910000/ |k 1/910000/912800/ |p 1 |x j | ||
| 999 | |a KXP-PPN1581252072 |e 3026442704 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"name":{"displayForm":["G. Pfeiffer, A.B. Fisker, E. Nebié, J. Hengelbrock, A. Sié, H. Becher, O. Müller"]},"type":{"media":"Online-Ressource","bibl":"article-journal"},"recId":"1581252072","id":{"doi":["10.1016/j.vaccine.2017.10.089"],"eki":["1581252072"]},"note":["Gesehen am 24.09.2018"],"origin":[{"dateIssuedKey":"2017","dateIssuedDisp":"15 November 2017"}],"person":[{"display":"Pfeiffer, Gillian","role":"aut","family":"Pfeiffer","given":"Gillian"},{"display":"Becher, Heiko","role":"aut","given":"Heiko","family":"Becher"},{"display":"Müller, Olaf","role":"aut","family":"Müller","given":"Olaf"}],"title":[{"subtitle":"a case control study nested into a health and demographic surveillance system in rural Burkina Faso","title":"Non-specific effects of childhood vaccinations","title_sort":"Non-specific effects of childhood vaccinations"}],"relHost":[{"disp":"Non-specific effects of childhood vaccinations a case control study nested into a health and demographic surveillance system in rural Burkina FasoVaccine","language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"title":[{"title_sort":"Vaccine","title":"Vaccine"}],"part":{"issue":"51","pages":"7114-7120","text":"35(2017), 51, Seite 7114-7120","extent":"7","year":"2017","volume":"35"},"recId":"266886078","pubHistory":["1.1983 -"],"id":{"zdb":["1468474-3"],"issn":["1873-2518"],"eki":["266886078"]},"note":["Gesehen am 19.10.07","Ungezählte Beil.: Supplement"],"origin":[{"dateIssuedDisp":"1983-","publisher":"Elsevier","publisherPlace":"Amsterdam","dateIssuedKey":"1983"}],"physDesc":[{"extent":"Online-Ressource"}]}],"physDesc":[{"extent":"7 S."}]} | ||
| SRT | |a PFEIFFERGINONSPECIFI1520 | ||