Deciphering the origin and evolution of hepatitis B viruses by means of a family of non-enveloped fish viruses
Summary: Hepatitis B viruses (HBVs), which are enveloped viruses with reverse-transcribed DNA genomes, constitute the family Hepadnaviridae. An outstanding feature of HBVs is their streamlined genome organization with extensive gene overlap. Remarkably, the ∼1,100 bp open reading frame (ORF) encodin...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
August 31, 2017
|
| In: |
Cell host and microbe
Year: 2017, Volume: 22, Issue: 3, Pages: 387-399.e6 |
| ISSN: | 1934-6069 |
| DOI: | 10.1016/j.chom.2017.07.019 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/j.chom.2017.07.019 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S1931312817303025 
|
| Author Notes: | Chris Lauber, Stefan Seitz, Simone Mattei, Alexander Suh, Jürgen Beck, Jennifer Herstein, Jacob Börold, Walter Salzburger, Lars Kaderali, John A. G. Briggs, and Ralf Bartenschlager |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1581285558 | ||
| 003 | DE-627 | ||
| 005 | 20240316100526.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 180925s2017 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.chom.2017.07.019 |2 doi | |
| 035 | |a (DE-627)1581285558 | ||
| 035 | |a (DE-576)511285558 | ||
| 035 | |a (DE-599)BSZ511285558 | ||
| 035 | |a (OCoLC)1341019113 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Lauber, Chris |d 1981- |e VerfasserIn |0 (DE-588)116780676X |0 (DE-627)1031307206 |0 (DE-576)511285221 |4 aut | |
| 245 | 1 | 0 | |a Deciphering the origin and evolution of hepatitis B viruses by means of a family of non-enveloped fish viruses |c Chris Lauber, Stefan Seitz, Simone Mattei, Alexander Suh, Jürgen Beck, Jennifer Herstein, Jacob Börold, Walter Salzburger, Lars Kaderali, John A. G. Briggs, and Ralf Bartenschlager |
| 264 | 1 | |c August 31, 2017 | |
| 300 | |a 19 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 25.09.2018 | ||
| 520 | |a Summary: Hepatitis B viruses (HBVs), which are enveloped viruses with reverse-transcribed DNA genomes, constitute the family Hepadnaviridae. An outstanding feature of HBVs is their streamlined genome organization with extensive gene overlap. Remarkably, the ∼1,100 bp open reading frame (ORF) encoding the envelope proteins is fully nested within the ORF of the viral replicase P. Here, we report the discovery of a diversified family of fish viruses, designated nackednaviruses, which lack the envelope protein gene, but otherwise exhibit key characteristics of HBVs including genome replication via protein-primed reverse-transcription and utilization of structurally related capsids. Phylogenetic reconstruction indicates that these two virus families separated more than 400 million years ago before the rise of tetrapods. We show that HBVs are of ancient origin, descending from non-enveloped progenitors in fishes. Their envelope protein gene emerged de novo, leading to a major transition in viral lifestyle, followed by co-evolution with their hosts over geologic eras. | ||
| 650 | 4 | |a hepadnaviruses | |
| 650 | 4 | |a hepatitis B virus | |
| 650 | 4 | |a overlapping open reading frames | |
| 650 | 4 | |a viral gene evolution | |
| 650 | 4 | |a virus discovery | |
| 650 | 4 | |a virus origins | |
| 650 | 4 | |a virus-host long-term co-evolution | |
| 700 | 1 | |a Seitz, Stefan |e VerfasserIn |0 (DE-588)1110073313 |0 (DE-627)864784627 |0 (DE-576)475719417 |4 aut | |
| 700 | 1 | |a Bartenschlager, Ralf |d 1958- |e VerfasserIn |0 (DE-588)1058097989 |0 (DE-627)796390509 |0 (DE-576)168706067 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cell host and microbe |d Amsterdam [u.a.] : Elsevier, 2007 |g 22(2017), 3, Seite 387-399.e6 |h Online-Ressource |w (DE-627)527572993 |w (DE-600)2276339-9 |w (DE-576)264425944 |x 1934-6069 |7 nnas |a Deciphering the origin and evolution of hepatitis B viruses by means of a family of non-enveloped fish viruses |
| 773 | 1 | 8 | |g volume:22 |g year:2017 |g number:3 |g pages:387-399.e6 |g extent:19 |a Deciphering the origin and evolution of hepatitis B viruses by means of a family of non-enveloped fish viruses |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.chom.2017.07.019 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u http://www.sciencedirect.com/science/article/pii/S1931312817303025 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20180925 | ||
| 993 | |a Article | ||
| 994 | |a 2017 | ||
| 998 | |g 1058097989 |a Bartenschlager, Ralf |m 1058097989:Bartenschlager, Ralf |d 910000 |d 911700 |d 700000 |d 718000 |e 910000PB1058097989 |e 911700PB1058097989 |e 700000PB1058097989 |e 718000PB1058097989 |k 0/910000/ |k 1/910000/911700/ |k 0/700000/ |k 1/700000/718000/ |p 11 |y j | ||
| 998 | |g 1110073313 |a Seitz, Stefan |m 1110073313:Seitz, Stefan |d 910000 |d 911700 |e 910000PS1110073313 |e 911700PS1110073313 |k 0/910000/ |k 1/910000/911700/ |p 2 | ||
| 999 | |a KXP-PPN1581285558 |e 3027142143 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"physDesc":[{"extent":"19 S."}],"note":["Gesehen am 25.09.2018"],"person":[{"family":"Lauber","roleDisplay":"VerfasserIn","display":"Lauber, Chris","role":"aut","given":"Chris"},{"family":"Seitz","roleDisplay":"VerfasserIn","given":"Stefan","role":"aut","display":"Seitz, Stefan"},{"display":"Bartenschlager, Ralf","role":"aut","given":"Ralf","family":"Bartenschlager","roleDisplay":"VerfasserIn"}],"origin":[{"dateIssuedKey":"2017","dateIssuedDisp":"August 31, 2017"}],"id":{"doi":["10.1016/j.chom.2017.07.019"],"eki":["1581285558"]},"relHost":[{"pubHistory":["1.2007 -"],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"part":{"pages":"387-399.e6","text":"22(2017), 3, Seite 387-399.e6","year":"2017","issue":"3","volume":"22","extent":"19"},"title":[{"title":"Cell host and microbe","title_sort":"Cell host and microbe"}],"disp":"Deciphering the origin and evolution of hepatitis B viruses by means of a family of non-enveloped fish virusesCell host and microbe","recId":"527572993","id":{"eki":["527572993"],"issn":["1934-6069"],"zdb":["2276339-9"]},"origin":[{"dateIssuedDisp":"2007-","publisher":"Elsevier","dateIssuedKey":"2007","publisherPlace":"Amsterdam [u.a.]"}],"note":["Gesehen am 20.11.2020"],"physDesc":[{"extent":"Online-Ressource"}]}],"recId":"1581285558","title":[{"title_sort":"Deciphering the origin and evolution of hepatitis B viruses by means of a family of non-enveloped fish viruses","title":"Deciphering the origin and evolution of hepatitis B viruses by means of a family of non-enveloped fish viruses"}],"name":{"displayForm":["Chris Lauber, Stefan Seitz, Simone Mattei, Alexander Suh, Jürgen Beck, Jennifer Herstein, Jacob Börold, Walter Salzburger, Lars Kaderali, John A. G. Briggs, and Ralf Bartenschlager"]},"language":["eng"],"type":{"media":"Online-Ressource","bibl":"article-journal"}} | ||
| SRT | |a LAUBERCHRIDECIPHERIN3120 | ||