Minor stroke syndromes in large-vessel occlusions: mechanical thrombectomy or thrombolysis only?
SUMMARY: While mechanical thrombectomy for large-vessel occlusions is now an evidence-based treatment, its efficacy and safety in minor stroke syndromes (NIHSS ≤ 5) is not proved. We identified, in our prospective data base, 378 patients with minor strokes in the anterior circulation; 54 (14.2%) of...
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
January 31, 2017
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| In: |
American journal of neuroradiology
Year: 2017, Jahrgang: 38, Heft: 6, Pages: 1177-1179 |
| ISSN: | 1936-959X |
| DOI: | 10.3174/ajnr.A5164 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.3174/ajnr.A5164 Verlag, Volltext: http://www.ajnr.org/content/38/6/1177 
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| Verfasserangaben: | M.P. Messer, S. Schönenberger, M.A. Möhlenbruch, J. Pfaff, C. Herweh, P.A. Ringleb, S. Nagel |
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| 520 | |a SUMMARY: While mechanical thrombectomy for large-vessel occlusions is now an evidence-based treatment, its efficacy and safety in minor stroke syndromes (NIHSS ≤ 5) is not proved. We identified, in our prospective data base, 378 patients with minor strokes in the anterior circulation; 54 (14.2%) of these had proved large-vessel occlusions. Eight of 54 (14.8%) were immediately treated with mechanical thrombectomy, 6/54 (11.1%) after early neurologic deterioration, and the rest were treated with standard thrombolysis only. Rates of successful recanalization were similar between the 2 mechanical thrombectomy groups (75% versus 100%). Rates of excellent outcome (modified Rankin Scale 0-1) were higher in patients with immediate thrombectomy (75%) compared with patients with delayed thrombectomy (33.3%) and thrombolysis only (55%). No symptomatic intracranial hemorrhage occurred in either group. These descriptive data are encouraging, and further analysis of large registries or even randomized controlled trials in this patient subgroup should be performed. | ||
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