Hepatitis B virus infection of HepaRG cells, HepaRG-hNTCP cells, and primary human hepatocytes

Here, we describe in detail how to technically perform HBV infection in vitro with these cells. The methods can be used to explore the mechanism of HBV infection and to build an antiviral screening platform suitable for evaluation of drug efficacy in cells that are metabolically close to primary hum...

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Bibliographische Detailangaben
Hauptverfasser: Ni, Yi (VerfasserIn) , Urban, Stephan (VerfasserIn)
Dokumenttyp: Kapitel/Artikel
Sprache:Englisch
Veröffentlicht: 2017
In: Hepatitis B Virus
Year: 2016, Pages: 15-25
DOI:10.1007/978-1-4939-6700-1_2
Online-Zugang:Resolving-System, Volltext: http://dx.doi.org/10.1007/978-1-4939-6700-1_2
Verlag, Volltext: https://link.springer.com/protocol/10.1007/978-1-4939-6700-1_2
Volltext
Verfasserangaben:Yi Ni, Stephan Urban
Beschreibung
Zusammenfassung:Here, we describe in detail how to technically perform HBV infection in vitro with these cells. The methods can be used to explore the mechanism of HBV infection and to build an antiviral screening platform suitable for evaluation of drug efficacy in cells that are metabolically close to primary human hepatocytes.
Beschreibung:First online: 15 December 2016
Gesehen am 27.09.2018
Beschreibung:Online Resource
ISBN:9781493967001
DOI:10.1007/978-1-4939-6700-1_2