Molecular genetic and functional association of Brugada and early repolarization syndromes with S422L missense mutation in KCNJ8

Background Adenosine triphosphate (ATP)-sensitive potassium cardiac channels consist of inward-rectifying channel subunits Kir6.1 or Kir6.2 (encoded by KCNJ8 or KCNJ11) and the sulfonylurea receptor subunits SUR2A (encoded by ABCC9). Objective To examine the association of mutations in KCNJ8 with Br...

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Bibliographische Detailangaben

Hauptverfasser:	Barajas-Martinez, Hector (VerfasserIn) , Veltmann, Christian (VerfasserIn) , Schimpf, Rainer (VerfasserIn) , Borggrefe, Martin (VerfasserIn)
Dokumenttyp:	Article (Journal)
Sprache:	Englisch
Veröffentlicht:	2012
In:	Heart rhythm Year: 2011, Jahrgang: 9, Heft: 4, Pages: 548-555
ISSN:	1556-3871
DOI:	10.1016/j.hrthm.2011.10.035
Online-Zugang:	Verlag, Volltext: http://dx.doi.org/10.1016/j.hrthm.2011.10.035 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S154752711101318X
Verfasserangaben:	Hector Barajas-Martínez, Dan Hu, Tania Ferrer, Carlos G. Onetti, Yuesheng Wu, Elena Burashnikov, Madalene Boyle, Tyler Surman, Janire Urrutia, Christian Veltmann, Rainer Schimpf, Martin Borggrefe, Christian Wolpert, Bassiema B. Ibrahim, José Antonio Sánchez-Chapula, Stephen Winters, Michel Haïssaguerre, Charles Antzelevitch