BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors
As major regulators of normal chondrogenesis, the bone morphogenic protein (BMP) and transforming growth factor β (TGFB) signaling pathways may be involved in the development and progression of central chondrosarcoma. In order to uncover their possible implication, the aim of this study was to perfo...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
22 October 2012
|
| In: |
BMC cancer
Year: 2012, Volume: 12 |
| ISSN: | 1471-2407 |
| DOI: | 10.1186/1471-2407-12-488 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/1471-2407-12-488 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/1471-2407-12-488 
|
| Author Notes: | Stephane Boeuf, Judith VMG Bovée, Burkhard Lehner, Brendy van den Akker, Maayke van Ruler, Anne-Marie Cleton-Jansen, and Wiltrud Richter |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1581706049 | ||
| 003 | DE-627 | ||
| 005 | 20220815025527.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 181010s2012 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1186/1471-2407-12-488 |2 doi | |
| 035 | |a (DE-627)1581706049 | ||
| 035 | |a (DE-576)511706049 | ||
| 035 | |a (DE-599)BSZ511706049 | ||
| 035 | |a (OCoLC)1341019823 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Boeuf, Stephane |e VerfasserIn |0 (DE-588)1167428234 |0 (DE-627)1031102582 |0 (DE-576)51113519X |4 aut | |
| 245 | 1 | 0 | |a BMP and TGFbeta pathways in human central chondrosarcoma |b enhanced endoglin and Smad 1 signaling in high grade tumors |c Stephane Boeuf, Judith VMG Bovée, Burkhard Lehner, Brendy van den Akker, Maayke van Ruler, Anne-Marie Cleton-Jansen, and Wiltrud Richter |
| 264 | 1 | |c 22 October 2012 | |
| 300 | |a 10 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 10.10.2018 | ||
| 520 | |a As major regulators of normal chondrogenesis, the bone morphogenic protein (BMP) and transforming growth factor β (TGFB) signaling pathways may be involved in the development and progression of central chondrosarcoma. In order to uncover their possible implication, the aim of this study was to perform a systematic quantitative study of the expression of BMPs, TGFBs and their receptors and to assess activity of the corresponding pathways in central chondrosarcoma. | ||
| 700 | 1 | |a Lehner, Burkhard |e VerfasserIn |0 (DE-588)1063147808 |0 (DE-627)810647311 |0 (DE-576)420525297 |4 aut | |
| 700 | 1 | |a Richter, Wiltrud |e VerfasserIn |0 (DE-588)1012822842 |0 (DE-627)704910780 |0 (DE-576)345982118 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t BMC cancer |d London : BioMed Central, 2001 |g 12(2012), Artikel-ID 488 |h Online-Ressource |w (DE-627)326643710 |w (DE-600)2041352-X |w (DE-576)107014645 |x 1471-2407 |7 nnas |a BMP and TGFbeta pathways in human central chondrosarcoma enhanced endoglin and Smad 1 signaling in high grade tumors |
| 773 | 1 | 8 | |g volume:12 |g year:2012 |g elocationid:488 |g extent:10 |a BMP and TGFbeta pathways in human central chondrosarcoma enhanced endoglin and Smad 1 signaling in high grade tumors |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1186/1471-2407-12-488 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://doi.org/10.1186/1471-2407-12-488 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20181010 | ||
| 993 | |a Article | ||
| 994 | |a 2012 | ||
| 998 | |g 1012822842 |a Richter, Wiltrud |m 1012822842:Richter, Wiltrud |d 910000 |d 911460 |e 910000PR1012822842 |e 911460PR1012822842 |k 0/910000/ |k 1/910000/911460/ |p 7 |y j | ||
| 998 | |g 1063147808 |a Lehner, Burkhard |m 1063147808:Lehner, Burkhard |d 910000 |d 911460 |e 910000PL1063147808 |e 911460PL1063147808 |k 0/910000/ |k 1/910000/911460/ |p 3 | ||
| 998 | |g 1167428234 |a Boeuf, Stephane |m 1167428234:Boeuf, Stephane |d 910000 |d 911460 |e 910000PB1167428234 |e 911460PB1167428234 |k 0/910000/ |k 1/910000/911460/ |p 1 |x j | ||
| 999 | |a KXP-PPN1581706049 |e 3028321696 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"media":"Online-Ressource","bibl":"article-journal"},"name":{"displayForm":["Stephane Boeuf, Judith VMG Bovée, Burkhard Lehner, Brendy van den Akker, Maayke van Ruler, Anne-Marie Cleton-Jansen, and Wiltrud Richter"]},"language":["eng"],"id":{"doi":["10.1186/1471-2407-12-488"],"eki":["1581706049"]},"physDesc":[{"extent":"10 S."}],"person":[{"family":"Boeuf","role":"aut","display":"Boeuf, Stephane","given":"Stephane"},{"role":"aut","display":"Lehner, Burkhard","given":"Burkhard","family":"Lehner"},{"role":"aut","given":"Wiltrud","display":"Richter, Wiltrud","family":"Richter"}],"title":[{"title":"BMP and TGFbeta pathways in human central chondrosarcoma","subtitle":"enhanced endoglin and Smad 1 signaling in high grade tumors","title_sort":"BMP and TGFbeta pathways in human central chondrosarcoma"}],"note":["Gesehen am 10.10.2018"],"origin":[{"dateIssuedKey":"2012","dateIssuedDisp":"22 October 2012"}],"relHost":[{"id":{"zdb":["2041352-X"],"eki":["326643710"],"issn":["1471-2407"]},"language":["eng"],"recId":"326643710","pubHistory":["1.2001 -"],"note":["Gesehen am 22.05.20"],"origin":[{"publisherPlace":"London ; Berlin ; Heidelberg","publisher":"BioMed Central ; Springer","dateIssuedDisp":"2001-","dateIssuedKey":"2001"}],"disp":"BMP and TGFbeta pathways in human central chondrosarcoma enhanced endoglin and Smad 1 signaling in high grade tumorsBMC cancer","physDesc":[{"extent":"Online-Ressource"}],"part":{"text":"12(2012), Artikel-ID 488","year":"2012","extent":"10","volume":"12"},"title":[{"title_sort":"BMC cancer","title":"BMC cancer"}],"type":{"media":"Online-Ressource","bibl":"periodical"}}],"recId":"1581706049"} | ||
| SRT | |a BOEUFSTEPHBMPANDTGFB2220 | ||