A20/TNFAIP3 discriminates tumor necrosis factor (TNF)-induced NF-[kappa]B from JNK pathway activation in hepatocytes
In the liver tumor necrosis factor (TNF)-induced signaling critically regulates the immune response of non-parenchymal cells as well as proliferation and apoptosis of hepatocytes via activation of the NF-κB and JNK pathways. Especially, the induction of negative feedback regulators such as IκBα and...
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| Hauptverfasser: | , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
23 August 2017
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| In: |
Frontiers in physiology
Year: 2017, Jahrgang: 8 |
| ISSN: | 1664-042X |
| DOI: | 10.3389/fphys.2017.00610 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.3389/fphys.2017.00610 Verlag, Volltext: https://www.frontiersin.org/articles/10.3389/fphys.2017.00610/full |
| Verfasserangaben: | Federico Pinna, Michaela Bissinger, Katharina Beuke, Nicolas Huber, Thomas Longerich, Ursula Kummer, Peter Schirmacher, Sven Sahle, and Kai Breuhahn |
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TNF-induced NF-[kappa]B signal transduction in the liver
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