Pulmonary, rhino-orbital and cutaneous mucormycosis caused by Rhizomucor pusillus in an immunocompromised patient

The number of patients with haematopoietic malignancies receiving chemotherapy and stem-cell transplantation has increased the incidence of severe opportunistic infections. Systemic fungal infections are of major concern in immunocompromised patients, as these infections are often fatal. We report a...

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Hauptverfasser: Hadaschik, Eva (VerfasserIn) , Koschny, Ronald (VerfasserIn) , Hallscheidt, Peter (VerfasserIn) , Enk, Alexander (VerfasserIn) , Hartschuh, Wolfgang (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 21 November 2011
In: Clinical and experimental dermatology
Year: 2012, Jahrgang: 37, Heft: 4, Pages: 355-357
ISSN:1365-2230
DOI:10.1111/j.1365-2230.2011.04235.x
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1111/j.1365-2230.2011.04235.x
Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2230.2011.04235.x
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Verfasserangaben:E. Hadaschik, R. Koschny, B. Willinger, P. Hallscheidt, A. Enk and W. Hartschuh

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520 |a The number of patients with haematopoietic malignancies receiving chemotherapy and stem-cell transplantation has increased the incidence of severe opportunistic infections. Systemic fungal infections are of major concern in immunocompromised patients, as these infections are often fatal. We report a case of a patient with acute myeloid leukaemia who developed multiple cutaneous plaques and necrotizing infiltrates in the lungs during chemotherapy. Using real-time PCR on a wax-embedded tissue sample, Rhizomucor pusillus was identified. We provide an overview of the literature on cutaneous mucormycosis and its diagnosis by PCR. 
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