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Chemokine analysis as a novel diagnostic modality in the early prediction of the outcome of non-union therapy: a matched pair analysis

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Despite the regenerative capability of skeletal tissue fracture, non-union is common. Treatment of non-unions remains challenging, and early determination of the outcome is impossible. Chemokines play an important role in promoting the formation of new bone and remodeling existing bone. Despite thei...

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Main Authors: Haubruck, Patrick (Author) , Hatzis, Anja (Author) , Heller, Raban (Author) , Daniel, Volker (Author) , Tanner, Michael Christopher (Author) , Moghaddam-Alvandi, Arash (Author) , Schmidmaier, Gerhard (Author) , Fischer, Christian (Author)
Format: Article (Journal)
Language:English
Published: 10 October 2018
In: Journal of orthopaedic surgery and research
Year: 2018, Volume: 13
ISSN:1749-799X
DOI:10.1186/s13018-018-0961-4
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13018-018-0961-4
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13018-018-0961-4
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Author Notes:Patrick Haubruck, Anja Solte, Raban Heller, Volker Daniel, Michael Tanner, Arash Moghaddam, Gerhard Schmidmaier and Christian Fischer
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Summary:Despite the regenerative capability of skeletal tissue fracture, non-union is common. Treatment of non-unions remains challenging, and early determination of the outcome is impossible. Chemokines play an important role in promoting the formation of new bone and remodeling existing bone. Despite their importance regarding the regulation of bone biology, the potential of chemokines as biological markers reflecting osseous regeneration is unknown.
Item Description:Gesehen am 16.10.2018
Physical Description:Online Resource
ISSN:1749-799X
DOI:10.1186/s13018-018-0961-4

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