Chemokine analysis as a novel diagnostic modality in the early prediction of the outcome of non-union therapy: a matched pair analysis

Despite the regenerative capability of skeletal tissue fracture, non-union is common. Treatment of non-unions remains challenging, and early determination of the outcome is impossible. Chemokines play an important role in promoting the formation of new bone and remodeling existing bone. Despite thei...

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Hauptverfasser: Haubruck, Patrick (VerfasserIn) , Hatzis, Anja (VerfasserIn) , Heller, Raban (VerfasserIn) , Daniel, Volker (VerfasserIn) , Tanner, Michael Christopher (VerfasserIn) , Moghaddam-Alvandi, Arash (VerfasserIn) , Schmidmaier, Gerhard (VerfasserIn) , Fischer, Christian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 10 October 2018
In: Journal of orthopaedic surgery and research
Year: 2018, Jahrgang: 13
ISSN:1749-799X
DOI:10.1186/s13018-018-0961-4
Online-Zugang:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13018-018-0961-4
Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13018-018-0961-4
Volltext
Verfasserangaben:Patrick Haubruck, Anja Solte, Raban Heller, Volker Daniel, Michael Tanner, Arash Moghaddam, Gerhard Schmidmaier and Christian Fischer
Beschreibung
Zusammenfassung:Despite the regenerative capability of skeletal tissue fracture, non-union is common. Treatment of non-unions remains challenging, and early determination of the outcome is impossible. Chemokines play an important role in promoting the formation of new bone and remodeling existing bone. Despite their importance regarding the regulation of bone biology, the potential of chemokines as biological markers reflecting osseous regeneration is unknown.
Beschreibung:Gesehen am 16.10.2018
Beschreibung:Online Resource
ISSN:1749-799X
DOI:10.1186/s13018-018-0961-4