Aggregation and Interaction of cationic nanoparticles on bacterial surfaces

Cationic monolayer-protected gold nanoparticles (AuNPs) with sizes of 6 or 2 nm interact with the cell membranes of Escherichia coli (Gram−) and Bacillus subtilis (Gram+), resulting in the formation of strikingly distinct AuNP surface aggregation patterns or lysis depending upon the size of the AuNP...

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Hauptverfasser: Hayden, Steven C. (VerfasserIn) , Bunz, Uwe H. F. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 25 April 2012
In: Journal of the American Chemical Society
Year: 2012, Jahrgang: 134, Heft: 16, Pages: 6920-6923
ISSN:1520-5126
DOI:10.1021/ja301167y
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1021/ja301167y
Verlag, Volltext: http://pubs.acs.org/doi/10.1021/ja301167y
Volltext
Verfasserangaben:Steven C. Hayden, Gengxiang Zhao, Krishnendu Saha, Ronnie L. Phillips, Xiaoning Li, Oscar R. Miranda, Vincent M. Rotello, Mostafa A. El-Sayed, Ingeborg Schmidt-Krey, and Uwe H.F. Bunz

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520 |a Cationic monolayer-protected gold nanoparticles (AuNPs) with sizes of 6 or 2 nm interact with the cell membranes of Escherichia coli (Gram−) and Bacillus subtilis (Gram+), resulting in the formation of strikingly distinct AuNP surface aggregation patterns or lysis depending upon the size of the AuNPs. The aggregation phenomena were investigated by transmission electron microscopy and UV−vis spectroscopy. Upon proteolytic treatment of the bacteria, the distinct aggregation patterns disappeared. 
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