Ledipasvir plus sofosbuvir fixed-dose combination for 6 weeks in patients with acute hepatitis C virus genotype 1 monoinfection (HepNet Acute HCV IV): an open-label, single-arm, phase 2 study
Background Early treatment of acute hepatitis C virus (HCV) infection with interferon alfa is highly effective, but can be associated with frequent side-effects. We investigated the safety and efficacy of an interferon-free regimen for treatment of acute HCV infection.
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2017
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| In: |
The lancet. Infectious diseases
Year: 2016, Volume: 17, Issue: 2, Pages: 215-222 |
| ISSN: | 1474-4457 |
| DOI: | 10.1016/S1473-3099(16)30408-X |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1016/S1473-3099(16)30408-X Verlag, Volltext: https://linkinghub.elsevier.com/retrieve/pii/S147330991630408X 
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| Author Notes: | Katja Deterding, Christoph D Spinner, Eckart Schott, Tania M Welzel, Guido Gerken, Hartwig Klinker, Ulrich Spengler, Johannes Wiegand, Julian Schulze zur Wiesch, Anita Pathil, Markus Cornberg, Andreas Umgelter, Caroline Zöllner, Stefan Zeuzem, Armin Papkalla, Kristina Weber, Svenja Hardtke, Heiko von der Leyen, Armin Koch, Dorothee von Witzendorff, Michael P Manns, Heiner Wedemeyer |
| Summary: | Background Early treatment of acute hepatitis C virus (HCV) infection with interferon alfa is highly effective, but can be associated with frequent side-effects. We investigated the safety and efficacy of an interferon-free regimen for treatment of acute HCV infection. |
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| Item Description: | Available online 28 October 2016 Gesehen am 19.10.2018 |
| Physical Description: | Online Resource |
| ISSN: | 1474-4457 |
| DOI: | 10.1016/S1473-3099(16)30408-X |