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High-affinity functional fluorescent ligands for human β-adrenoceptors

Visualization of the G-protein coupled receptor (GPCR) is of great importance for studying its function in a native cell. We have synthesized a series of red-emitting fluorescent probes targeting β-adrenergic receptor (βAR) that are compatible with confocal and Stimulated Emission Depletion (STED) m...

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Hauptverfasser: Mitronova, Gyuzel Yu (VerfasserIn) , Hell, Stefan (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 26 September 2017
In: Scientific reports
Year: 2017, Jahrgang: 7
ISSN:2045-2322
DOI:10.1038/s41598-017-12468-3
Online-Zugang:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1038/s41598-017-12468-3
Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41598-017-12468-3
Volltext
Verfasserangaben:Gyuzel Y. Mitronova, Gražvydas Lukinavičius, Alexey N. Butkevich, Tobias Kohl, Vladimir N. Belov, Stephan E. Lehnart & Stefan W. Hell

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