Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals
Background: The genetic etiology of human lipid quantitative traits is not fully elucidated, and interactions between variants may play a role. We performed a gene-centric interaction study for four different lipid traits: low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholest...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
24 July 2017
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| In: |
BioData Mining
Year: 2017, Volume: 10 |
| ISSN: | 1756-0381 |
| DOI: | 10.1186/s13040-017-0145-5 |
| Online Access: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1186/s13040-017-0145-5 Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13040-017-0145-5 
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| Author Notes: | Emily R. Holzinger, Shefali S. Verma, Carrie B. Moore, Molly Hall, Rishika De, Diane Gilbert-Diamond, Matthew B. Lanktree, Nathan Pankratz, Antoinette Amuzu, Amber Burt, Caroline Dale, Scott Dudek, Clement E. Furlong, Tom R. Gaunt, Daniel Seung Kim, Helene Riess, Suthesh Sivapalaratnam, Vinicius Tragante, Erik P.A. van Iperen, Ariel Brautbar, David S. Carrell, David R. Crosslin, Gail P. Jarvik, Helena Kuivaniemi, Iftikhar J. Kullo, Eric B. Larson, Laura J. Rasmussen-Torvik, Gerard Tromp, Jens Baumert, Karen J. Cruickshanks, Martin Farrall, Aroon D. Hingorani, G.K. Hovingh, Marcus E. Kleber, Barbara E. Klein, Ronald Klein, Wolfgang Koenig, Leslie A. Lange, Winfried Mӓrz, Kari E. North, N. Charlotte Onland-Moret, Alex P. Reiner, Philippa J. Talmud, Yvonne T. van der Schouw, James G. Wilson, Mika Kivimaki, Meena Kumari, Jason H. Moore, Fotios Drenos, Folkert W. Asselbergs, Brendan J. Keating and Marylyn D. Ritchie |
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Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals
BioMed Central 2017
Article (Journal)
Book/Monograph
Online Resource