DCE‐MRI of the human kidney using BLADE: a feasibility study in healthy volunteers
Purpose: To evaluate the degree of motion compensation in the kidney using two different sampling methods, each in their optimized settings: A BLADE k‐space acquisition technique and a routinely used kidney perfusion acquisition scheme (TurboFLASH). Materials and Methods: Dynamic contrast enhanced m...
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| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2012
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| In: |
Journal of magnetic resonance imaging
Year: 2012, Jahrgang: 35, Heft: 4, Pages: 868-874 |
| ISSN: | 1522-2586 |
| DOI: | 10.1002/jmri.23509 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1002/jmri.23509 Verlag, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jmri.23509 
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| Verfasserangaben: | Florian Lietzmann, Frank G. Zöllner, Ulrike I. Attenberger, Stefan Haneder, Henrik J. Michaely, and Lothar R. Schad |
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| 245 | 1 | 0 | |a DCE‐MRI of the human kidney using BLADE |b a feasibility study in healthy volunteers |c Florian Lietzmann, Frank G. Zöllner, Ulrike I. Attenberger, Stefan Haneder, Henrik J. Michaely, and Lothar R. Schad |
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| 520 | |a Purpose: To evaluate the degree of motion compensation in the kidney using two different sampling methods, each in their optimized settings: A BLADE k‐space acquisition technique and a routinely used kidney perfusion acquisition scheme (TurboFLASH). Materials and Methods: Dynamic contrast enhanced magnetic resonance examinations were performed in 16 healthy volunteers on a 3 Tesla MR‐system with two parameterizations of the BLADE sequence and the standard reference acquisition scheme. Signal intensity enhanced time curves were analyzed with a mathematical model and a widely published separable compartment model on cortex regions to assess robustness versus motion artifacts. Results: BLADE‐measurements with a strip‐width of 32 lines constituted the smallest mean values for the sum of squared errors (6065 ± 4996) compared with the measurement with a strip‐width of 64 lines (13849 ± 14079) or the standard TurboFLASH (11884 ± 8076). Calculations concerning goodness of the fit of the applied compartment model yielded an overall average of the Akaike Fit Error of 732 ± 141 for BLADE (646 ± 149 for a strip‐width of 32 lines, 816 ± 53 for 64 lines) and 1626 ± 303 for the TurboFLASH (TFL) sequence. Conclusion: We demonstrated that renal dynamic contrast enhanced magnetic resonance imaging using BLADE k‐space sampling with a strip‐width of 32 is significantly less sensitive to motion than a widely published Turbo‐Flash sequence with nearly similar parameters. | ||
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