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Iron induces anti-tumor activity in tumor-associated macrophages

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Tumor-associated macrophages (TAMs) frequently help to sustain tumor growth and mediate immune suppression in the tumor microenvironment. Here we identified a subset of iron-loaded, pro-inflammatory TAMs localized in hemorrhagic areas of the tumor microenvironment. The occurrence of iron-loaded TAMs...

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Main Authors: Costa da Silva, Milene (Author) , Breckwoldt, Michael O. (Author) , Vinchi, Francesca (Author) , Thielmann, Carl Maximilian (Author) , Meister, Michael (Author) , Muley, Thomas (Author) , Warth, Arne (Author) , Platten, Michael (Author) , Hentze, Matthias W. (Author) , Muckenthaler, Martina (Author)
Format: Article (Journal)
Language:English
Published: 08 November 2017
In: Frontiers in immunology
Year: 2017, Volume: 8
ISSN:1664-3224
DOI:10.3389/fimmu.2017.01479
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.3389/fimmu.2017.01479
Verlag, kostenfrei, Volltext: https://www.frontiersin.org/articles/10.3389/fimmu.2017.01479/full
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Author Notes:Milene Costa da Silva, Michael O. Breckwoldt, Francesca Vinchi, Margareta P. Correia, Ana Stojanovic, Carl Maximilian Thielmann, Michael Meister, Thomas Muley, Arne Warth, Michael Platten, Matthias W. Hentze, Adelheid Cerwenka and Martina U. Muckenthaler
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Iron induces anti-tumor activity in tumor-associated macrophages by Costa da Silva, Milene (Author) , Breckwoldt, Michael O. (Author) , Vinchi, Francesca (Author) , Thielmann, Carl Maximilian (Author) , Meister, Michael (Author) , Muley, Thomas (Author) , Warth, Arne (Author) , Platten, Michael (Author) , Hentze, Matthias W. (Author) , Cerwenka, Adelheid (Author) , Muckenthaler, Martina (Author) ,


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