Iron induces anti-tumor activity in tumor-associated macrophages
Tumor-associated macrophages (TAMs) frequently help to sustain tumor growth and mediate immune suppression in the tumor microenvironment. Here we identified a subset of iron-loaded, pro-inflammatory TAMs localized in hemorrhagic areas of the tumor microenvironment. The occurrence of iron-loaded TAMs...
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| Hauptverfasser: | , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
08 November 2017
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| In: |
Frontiers in immunology
Year: 2017, Jahrgang: 8 |
| ISSN: | 1664-3224 |
| DOI: | 10.3389/fimmu.2017.01479 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: http://dx.doi.org/10.3389/fimmu.2017.01479 Verlag, kostenfrei, Volltext: https://www.frontiersin.org/articles/10.3389/fimmu.2017.01479/full |
| Verfasserangaben: | Milene Costa da Silva, Michael O. Breckwoldt, Francesca Vinchi, Margareta P. Correia, Ana Stojanovic, Carl Maximilian Thielmann, Michael Meister, Thomas Muley, Arne Warth, Michael Platten, Matthias W. Hentze, Adelheid Cerwenka and Martina U. Muckenthaler |
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