Multidetector computed tomography virtual cystoscopy: an effective diagnostic tool in patients with hematuria

Objective: To evaluate the efficacy and the potential use of multidetector computed tomography virtual cystoscopy (MDCT-VC) in patients with gross hematuria. Methods: A total of 32 patients underwent MDCT-VC, cystoscopy, and a cytologic examination. The slice thickness of MDCT was 1 mm. Bladder dist...

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Bibliographic Details
Main Authors: Kühhas, Franklin (Author) , Tosev, Georgi (Author)
Format: Article (Journal)
Language:English
Published: 3 February 2012
In: Urology
Year: 2012, Volume: 79, Issue: 2, Pages: 270-276
ISSN:1527-9995
DOI:10.1016/j.urology.2011.10.011
Online Access:Verlag, Volltext: http://dx.doi.org/10.1016/j.urology.2011.10.011
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0090429511024848
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Author Notes:Franklin Emmanuel Kuehhas, Peter Weibl, Georgi Tosev, Georg Schatzl, and Gertraud Heinz-Peer

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520 |a Objective: To evaluate the efficacy and the potential use of multidetector computed tomography virtual cystoscopy (MDCT-VC) in patients with gross hematuria. Methods: A total of 32 patients underwent MDCT-VC, cystoscopy, and a cytologic examination. The slice thickness of MDCT was 1 mm. Bladder distension was done with room air. The data were converted into 3-dimensional virtual reconstructive models. The data sets were reviewed independently by 2 experienced radiologists. Tumors confined to the mucosa, infiltrating the muscularis, and transmural tumors were distinguished. Results: VC showed a sensitivity and specificity of 100%. The radiologic accuracy regarding T stage correlated in 87.5%. MDCT-VC identified 21 bladder lesions suspicious for bladder cancer in 18 patients. The histologic results showed 22 patients with bladder lesions, 18 were diagnosed with transitional cell carcinoma of the bladder, 3 had bladder endometriosis, and 1 had an infiltrating colon cancer. Four patients had concomitant carcinoma in situ lesions, which were not seen completely with MDCT-VC. However, cytology was positive in those cases. Ten patients did not have any tumor signs on VC and the subsequent conventional cystoscopy did not bring any change to the initial tumor-free diagnosis of VC. Conclusion: MDCT-VC combined with urine cytology is a good alternative to conventional cystoscopy for patients with painless gross hematuria. It should be used as a decision-making aid to identify patients who will benefit from additional cystoscopic examination. Future developments should focus on the visibility of sessile and carcinoma in situ lesions. 
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