Helping EGFR inhibition to block cancer
Effectiveness of EGFR treatment is impaired through an early adaptive response. TNF-JNK-Axl-ERK signaling contributes to this primary resistance to EGFR inhibition and might serve as novel target to improve EGFR inhibition.
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
26 July 2017
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| In: |
Nature neuroscience
Year: 2017, Jahrgang: 20, Heft: 8, Pages: 1035-1037 |
| ISSN: | 1546-1726 |
| DOI: | 10.1038/nn.4605 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1038/nn.4605 Verlag, Volltext: https://www.nature.com/articles/nn.4605 
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| Verfasserangaben: | Rolf Warta & Christel Herold-Mende |
| Zusammenfassung: | Effectiveness of EGFR treatment is impaired through an early adaptive response. TNF-JNK-Axl-ERK signaling contributes to this primary resistance to EGFR inhibition and might serve as novel target to improve EGFR inhibition. |
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| Beschreibung: | Gesehen am 28.11.2018 |
| Beschreibung: | Online Resource |
| ISSN: | 1546-1726 |
| DOI: | 10.1038/nn.4605 |