Buchumschlag

Trial design on prophylaxis and treatment of brain metastases: lessons learned from the EORTC Brain Metastases Strategic Meeting 2012

Brain metastases (BM) occur in a significant proportion of cancer patients and are associated with considerable morbidity and poor prognosis. The trial design in BM patients is particularly challenging, as many disease and patient variables, statistical issues, and the selection of appropriate end-p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Preusser, Matthias (VerfasserIn) , Winkler, Frank (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: December 2012
In: European journal of cancer
Year: 2012, Jahrgang: 48, Heft: 18, Pages: 3439-3447
ISSN:1879-0852
DOI:10.1016/j.ejca.2012.07.002
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1016/j.ejca.2012.07.002
Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S0959804912005485
Volltext
Verfasserangaben:Matthias Preusser, Frank Winkler, Laurence Collette, Sven Haller, Sandrine Marreaud, Riccardo Soffietti, Martin Klein, Jaap C. Reijneveld, Jörg-Christian Tonn, Brigitta G. Baumert, Paula Mulvenna, Dirk Schadendorf, Renata Duchnowska, Anna Sophie Berghoff, Nancy Lin, David A. Cameron, Yazid Belkacemi, Jacek Jassem, Damien C. Weber
Beschreibung
Zusammenfassung:Brain metastases (BM) occur in a significant proportion of cancer patients and are associated with considerable morbidity and poor prognosis. The trial design in BM patients is particularly challenging, as many disease and patient variables, statistical issues, and the selection of appropriate end-points have to be taken into account. During a meeting organised on behalf of the European Organisation for Research and Treatment of Cancer (EORTC), methodological aspects of trial design in BM were discussed. This paper summarises the issues and potential trial strategies discussed during this meeting and may provide some guidance for the design of trials in BM patients.
Beschreibung:Gesehen am 28.11.2018
Beschreibung:Online Resource
ISSN:1879-0852
DOI:10.1016/j.ejca.2012.07.002

Ähnliche Einträge