Immune defense against S. Epidermidis biofilms: components of the extracellular polymeric substance activate distinct bactericidal mechanisms of phagocytic cells
Bacteria, organized in biofilms, are a common cause of relapsing or persistent infections and the ultimate cause of implant-associated osteomyelitis. Bacterial biofilms initiate a prominent local inflammatory response with infiltration of polymorphonuclear neutrophils (PMN), the main protagonists of...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
December 10, 2012
|
| In: |
The international journal of artificial organs
Year: 2012, Jahrgang: 35, Heft: 10, Pages: 700-712 |
| ISSN: | 1724-6040 |
| DOI: | 10.5301/ijao.5000151 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.5301/ijao.5000151 Verlag, Volltext: https://doi.org/10.5301/ijao.5000151 
|
| Verfasserangaben: | Eva Meyle, Gerald Brenner-Weiss, Ursula Obst, Birgit Prior, G. Maria Hänsch |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 158461496X | ||
| 003 | DE-627 | ||
| 005 | 20230427161334.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 181129s2012 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.5301/ijao.5000151 |2 doi | |
| 035 | |a (DE-627)158461496X | ||
| 035 | |a (DE-576)51461496X | ||
| 035 | |a (DE-599)BSZ51461496X | ||
| 035 | |a (OCoLC)1341024434 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Meyle, Eva |d 1983- |e VerfasserIn |0 (DE-588)1037752163 |0 (DE-627)756000300 |0 (DE-576)391784420 |4 aut | |
| 245 | 1 | 0 | |a Immune defense against S. Epidermidis biofilms |b components of the extracellular polymeric substance activate distinct bactericidal mechanisms of phagocytic cells |c Eva Meyle, Gerald Brenner-Weiss, Ursula Obst, Birgit Prior, G. Maria Hänsch |
| 264 | 1 | |c December 10, 2012 | |
| 300 | |a 13 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 29.11.2018 | ||
| 520 | |a Bacteria, organized in biofilms, are a common cause of relapsing or persistent infections and the ultimate cause of implant-associated osteomyelitis. Bacterial biofilms initiate a prominent local inflammatory response with infiltration of polymorphonuclear neutrophils (PMN), the main protagonists of the local innate host defense against bacteria. In our previous work we found that PMN recognize and adhere to biofilms, and that phagocytosis and degranulation of bactericidal substances, such as lactoferrin, were initiated. In contrast to the situation with planktonic bacteria, opsonization of biofilms with immunoglobulin and complement was not required for PMN activation, suggesting that biofilms contain signaling components for PMN. In the present study we identified in the bacteria-free extracellular substance of Staphylococcus epidermidis biofilms protein fractions that activated PMN in vitro. | ||
| 700 | 1 | |a Brenner-Weiß, Gerald |e VerfasserIn |0 (DE-588)122393134X |0 (DE-627)1743478038 |4 aut | |
| 700 | 1 | |a Obst, Ursula |e VerfasserIn |0 (DE-588)1212634799 |0 (DE-627)1702185192 |4 aut | |
| 700 | 1 | |a Prior, Birgit |e VerfasserIn |0 (DE-588)1078649200 |0 (DE-627)839016107 |0 (DE-576)451587154 |4 aut | |
| 700 | 1 | |a Hänsch, Gertrud Maria |e VerfasserIn |0 (DE-588)1032383380 |0 (DE-627)738394076 |0 (DE-576)323810926 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The international journal of artificial organs |d Thousand Oaks, CA : Sage Publishing, 1978 |g 35(2012), 10, Seite 700-712 |h Online-Ressource |w (DE-627)269534431 |w (DE-600)1474999-3 |w (DE-576)398099758 |x 1724-6040 |7 nnas |a Immune defense against S. Epidermidis biofilms components of the extracellular polymeric substance activate distinct bactericidal mechanisms of phagocytic cells |
| 773 | 1 | 8 | |g volume:35 |g year:2012 |g number:10 |g pages:700-712 |g extent:13 |a Immune defense against S. Epidermidis biofilms components of the extracellular polymeric substance activate distinct bactericidal mechanisms of phagocytic cells |
| 856 | 4 | 0 | |u http://dx.doi.org/10.5301/ijao.5000151 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://doi.org/10.5301/ijao.5000151 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20181129 | ||
| 993 | |a Article | ||
| 994 | |a 2012 | ||
| 998 | |g 1032383380 |a Hänsch, Gertrud Maria |m 1032383380:Hänsch, Gertrud Maria |d 910000 |d 911600 |e 910000PH1032383380 |e 911600PH1032383380 |k 0/910000/ |k 1/910000/911600/ |p 5 |y j | ||
| 998 | |g 1078649200 |a Prior, Birgit |m 1078649200:Prior, Birgit |d 910000 |d 911600 |e 910000PP1078649200 |e 911600PP1078649200 |k 0/910000/ |k 1/910000/911600/ |p 4 | ||
| 998 | |g 1037752163 |a Meyle, Eva |m 1037752163:Meyle, Eva |d 910000 |d 911600 |e 910000PM1037752163 |e 911600PM1037752163 |k 0/910000/ |k 1/910000/911600/ |p 1 |x j | ||
| 999 | |a KXP-PPN158461496X |e 3035950903 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"physDesc":[{"extent":"13 S."}],"relHost":[{"title":[{"title_sort":"international journal of artificial organs","subtitle":"IJAO","title":"The international journal of artificial organs"}],"titleAlt":[{"title":"IJAO"},{"title":"JAO"}],"part":{"pages":"700-712","issue":"10","year":"2012","extent":"13","volume":"35","text":"35(2012), 10, Seite 700-712"},"pubHistory":["1.1978 -"],"recId":"269534431","language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Immune defense against S. Epidermidis biofilms components of the extracellular polymeric substance activate distinct bactericidal mechanisms of phagocytic cellsThe international journal of artificial organs","note":["Gesehen am 06.03.2020"],"id":{"issn":["1724-6040"],"eki":["269534431"],"zdb":["1474999-3"]},"origin":[{"publisherPlace":"Thousand Oaks, CA ; Milano","dateIssuedKey":"1978","publisher":"Sage Publishing ; Wichtig","dateIssuedDisp":"1978-"}],"name":{"displayForm":["official journal of European Society for Artifical Organs"]},"physDesc":[{"extent":"Online-Ressource"}]}],"origin":[{"dateIssuedKey":"2012","dateIssuedDisp":"December 10, 2012"}],"id":{"eki":["158461496X"],"doi":["10.5301/ijao.5000151"]},"name":{"displayForm":["Eva Meyle, Gerald Brenner-Weiss, Ursula Obst, Birgit Prior, G. Maria Hänsch"]},"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 29.11.2018"],"language":["eng"],"recId":"158461496X","title":[{"subtitle":"components of the extracellular polymeric substance activate distinct bactericidal mechanisms of phagocytic cells","title":"Immune defense against S. Epidermidis biofilms","title_sort":"Immune defense against S. Epidermidis biofilms"}],"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Meyle, Eva","given":"Eva","family":"Meyle"},{"given":"Gerald","family":"Brenner-Weiß","role":"aut","roleDisplay":"VerfasserIn","display":"Brenner-Weiß, Gerald"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Obst, Ursula","given":"Ursula","family":"Obst"},{"family":"Prior","given":"Birgit","roleDisplay":"VerfasserIn","display":"Prior, Birgit","role":"aut"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Hänsch, Gertrud Maria","given":"Gertrud Maria","family":"Hänsch"}]} | ||
| SRT | |a MEYLEEVABRIMMUNEDEFE1020 | ||