Secreted frizzled-related protein 2 (sFRP2) redirects non-canonical Wnt signaling from Fz7 to Ror2 during vertebrate gastrulation

Convergent extension movements during vertebrate gastrulation require a balanced activity of non-canonical Wnt signaling pathways, but the factors regulating this interplay on the molecular level are poorly characterized. Here we show that sFRP2, a member of the secreted frizzled-related protein (sF...

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Bibliographic Details

Main Authors:	Brinkmann, Eva-Maria (Author) , Kumar, Rahul (Author) , Steinbeisser, Herbert (Author) , Kaufmann, Lilian (Author) , Özbek, Suat (Author)
Format:	Article (Journal)
Language:	English
Published:	April 20, 2016
In:	The journal of biological chemistry Year: 2016, Volume: 291, Issue: 26, Pages: 13730-13742
ISSN:	1083-351X
DOI:	10.1074/jbc.M116.733766
Online Access:	Verlag, Volltext: http://dx.doi.org/10.1074/jbc.M116.733766 Verlag, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919455/
Author Notes:	Eva-Maria Brinkmann, Benjamin Mattes, Rahul Kumar, Anja I. H. Hagemann, Dietmar Gradl, Steffen Scholpp, Herbert Steinbeisser, Lilian T. Kaufmann, and Suat Özbek