Blood pressure percentiles in 22,051 German children and adolescents: the PEP Family Heart Study
Background: Strong associations between blood pressure (BP) and overweight raise the question whether overweight children (body mass index (BMI) ≥85th percentile) should be included in the normative database. Methods: Using the LMS (Lamda-Mu-Sigma) method, we developed age-, gender-, and height-adju...
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
May 2015
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| In: |
American journal of hypertension
Year: 2015, Jahrgang: 28, Heft: 5, Pages: 672-679 |
| ISSN: | 1941-7225 |
| DOI: | 10.1093/ajh/hpu208 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1093/ajh/hpu208 Verlag, Volltext: https://academic.oup.com/ajh/article/28/5/672/2743370 |
| Verfasserangaben: | Peter Schwandt, Juergen E. Scholze, Thomas Bertsch, Evelyn Liepold, and Gerda M. Haas |
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| 245 | 1 | 0 | |a Blood pressure percentiles in 22,051 German children and adolescents |b the PEP Family Heart Study |c Peter Schwandt, Juergen E. Scholze, Thomas Bertsch, Evelyn Liepold, and Gerda M. Haas |
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| 520 | |a Background: Strong associations between blood pressure (BP) and overweight raise the question whether overweight children (body mass index (BMI) ≥85th percentile) should be included in the normative database. Methods: Using the LMS (Lamda-Mu-Sigma) method, we developed age-, gender-, and height-adjusted percentile curves for systolic blood pressure (SBP) and diastolic blood pressure (DBP) at the 50th, 85th, 90th, 95th, and 97th percentiles in 22,051 German youths (18,917 normal-weight, 1,938 overweight, and 1,196 obese) aged 3-18 years from yearly cross-sectional surveys of the PEP Family Heart Study Nuremberg. Results: Among children, we found no gender differences for BP and BMI. Male adolescents are taller and heavier. The mean prevalence of hypertension and obesity is 7.3% and 5.2% among children and 7.2% and 5.8% among adolescents, respectively. The prevalence of elevated BP increased substantially by weight groups achieving 24.4% in obese females and 21.9% in obese males with odds ratios of 5.9 (95% confidence interval (CI): 5.1-7.5) and 4.3 (95% CI: 3.5-5.2), respectively. The shapes of the 10 LMS-smoothed SBP and DBP percentile curves differ substantially between gender and weight group. The normal-weight percentiles are nearly identical with the overall growth charts, but separate percentiles for overweight and obese youths provide considerably higher values, such as 148/91 vs. 136/86 mm Hg for a 17-year-old male and 136/91 vs. 123/81 mm Hg for female, respectively, at the 90th percentile. Conclusions: Because of substantially higher BP percentiles, separate databases for overweight and obese children and adolescents are strongly recommended. | ||
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