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Evidence for PTGER4, PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level

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Genetic associations between variants on chromosome 5p13 and 8q24 and gastric cancer (GC) have been previously reported in the Asian population. We aimed to replicate these findings and to characterize the associations at the genome and transcriptome level. We performed a fine‐mapping association st...

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Main Authors: Heinrichs, Sophie K. M. (Author) , Schmidt, Thomas (Author) , Brenner, Hermann (Author) , Butterbach, Katja (Author)
Format: Article (Journal)
Language:English
Published: October 2018
In: Cancer medicine
Year: 2018, Volume: 7, Issue: 10, Pages: 5057-5065
ISSN:2045-7634
DOI:10.1002/cam4.1719
Online Access:Verlag, kostenfrei, Volltext: http://dx.doi.org/10.1002/cam4.1719
Verlag, kostenfrei, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198243/
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Author Notes:Sophie K.M. Heinrichs, Timo Hess, Jessica Becker, Lutz Hamann, Yogesh K. Vashist, Katja Butterbach, Thomas Schmidt, Hakan Alakus, Iurii Krasniuk, Aksana Höblinger, Philipp Lingohr, Monika Ludwig, Alexander F. Hagel, Claus W. Schildberg, Lothar Veits, Ugne Gyvyte, Katharina Weise, Vitalia Schüller, Anne C. Böhmer, Julia Schröder, Jan Gehlen, Nicole Kreuser, Sebastian Hofer, Hauke Lang, Florian Lordick, Peter Malfertheiner, Markus Moehler, Oliver Pech, Nikolaos Vassos, Ernst Rodermann, Jakob R. Izbicki, Martin Kruschewski, Katja Ott, Ralf R. Schumann, Michael Vieth, Elisabeth Mangold, Evita Gasenko, Limas Kupcinskas, Hermann Brenner, Peter Grimminger, Luis Bujanda, Federico Sopeña, Jesús Espinel, Concha Thomson, Ángeles Pérez‐Aísa, Rafael Campo, Fernando Geijo, Daniela Collette, Christiane Bruns, Katharina Messerle, Ines Gockel, Markus M. Nöthen, Hans Lippert, Karsten Ridwelski, Angel Lanas, Gisela Keller, Michael Knapp, Marcis Leja, Juozas Kupcinskas, Maria A. García‐González, Marino Venerito, Johannes Schumacher
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Evidence for PTGER4,PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level by Heinrichs, Sophie K. M. (Author) , Heß, Timo (Author) , Becker, Jessica (Author) , Hamann, Lutz (Author) , Vashist, Yogesh K. (Author) , Butterbach, Katja (Author) , Schmidt, Thomas (Author) , Alakus, Hakan (Author) , Krasniuk, Iurii (Author) , Höblinger, Aksana (Author) , Lingohr, Philipp (Author) , Ludwig, Monika (Author) , Hagel, Alexander F. (Author) , Schildberg, Claus (Author) , Veits, Lothar (Author) , Gyvyte, Ugne (Author) , Weise, Katharina (Author) , Schüller, Vitalia (Author) , Böhmer, Anne C. (Author) , Schröder, Julia (Author) , Gehlen, Jan (Author) , Kreuser, Nicole (Author) , Hofer, Sebastian (Author) , Lang, Hauke (Author) , Lordick, Florian (Author) , Malfertheiner, Peter (Author) , Möhler, Markus (Author) , Pech, Oliver (Author) , Vassos, Nikolaos (Author) , Rodermann, Ernst Michael (Author) , Izbicki, Jakob R. (Author) , Kruschewski, Martin (Author) , Ott, Katja (Author) , Schumann, Ralf R. (Author) , Vieth, Michael (Author) , Mangold, Elisabeth (Author) , Gasenko, Evita (Author) , Kupcinskas, Limas (Author) , Brenner, Hermann (Author) , Grimminger, Peter (Author) , Bujanda, Luis (Author) , Sopeña, Federico (Author) , Espinel, Jesús (Author) , Thomson, Concha (Author) , Pérez‐Aísa, Ángeles (Author) , Campo, Rafael (Author) , Geijo, Fernando (Author) , Collette, Daniela (Author) , Bruns, Christiane (Author) , Messerle, Katharina (Author) , Gockel, Ines (Author) , Nöthen, Markus Maria (Author) , Lippert, Hans (Author) , Ridwelski, Karsten (Author) , Lanas Arbeloa, Ángel (Author) , Keller, Gisela (Author) , Knapp, Michael (Author) , Leja, Marcis (Author) , Kupčinskas, Juozas (Author) , García‐González, Maria A. (Author) , Venerito, Marino (Author) , Schumacher, Johannes (Author) ,


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Evidence for PTGER4, PSCA and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level by Heß, Timo (Author) , Vashist, Yogesh K. (Author) , Schmidt, Thomas (Author) , Lingohr, Philipp (Author) , Hagel, Alexander F. (Author) , Schildberg, Claus (Author) , Veits, Lothar (Author) , González-Carmona, María Á. (Author) , Lordick, Florian (Author) , Malfertheiner, Peter (Author) , Möhler, Markus (Author) , Pech, Oliver (Author) , Rodermann, Ernst Michael (Author) , Izbicki, Jakob R. (Author) , Ott, Katja (Author) , Vieth, Michael (Author) , Mangold, Elisabeth (Author) , Brenner, Hermann (Author) , Grimminger, Peter (Author) , Bruns, Christiane (Author) , Büchler, Markus W. (Author) , Gockel, Ines (Author) , Nöthen, Markus Maria (Author) , Lippert, Hans (Author) , Ridwelski, Karsten (Author) , Leja, Marcis (Author) , Kupčinskas, Juozas (Author) , Venerito, Marino (Author) ,


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