Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6
CDK6 directly regulates transcription of FLT3 and PIM1 in a kinase-dependent manner.
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
April 20, 2016
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| In: |
Blood
Year: 2016, Jahrgang: 127, Heft: 23, Pages: 2890-2902 |
| ISSN: | 1528-0020 |
| DOI: | 10.1182/blood-2015-11-683581 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1182/blood-2015-11-683581 Verlag, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920675/ |
| Verfasserangaben: | Iris Z. Uras, Gina J. Walter, Ruth Scheicher, Florian Bellutti, Michaela Prchal-Murphy, Anca S. Tigan, Peter Valent, Florian H. Heidel, Stefan Kubicek, Claudia Scholl, Stefan Fröhling and Veronika Sexl |
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