Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6

CDK6 directly regulates transcription of FLT3 and PIM1 in a kinase-dependent manner.

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Bibliographische Detailangaben
Hauptverfasser: Uras, Iris Z. (VerfasserIn) , Scholl, Claudia (VerfasserIn) , Fröhling, Stefan (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: April 20, 2016
In: Blood
Year: 2016, Jahrgang: 127, Heft: 23, Pages: 2890-2902
ISSN:1528-0020
DOI:10.1182/blood-2015-11-683581
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1182/blood-2015-11-683581
Verlag, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920675/
Volltext
Verfasserangaben:Iris Z. Uras, Gina J. Walter, Ruth Scheicher, Florian Bellutti, Michaela Prchal-Murphy, Anca S. Tigan, Peter Valent, Florian H. Heidel, Stefan Kubicek, Claudia Scholl, Stefan Fröhling and Veronika Sexl

MARC

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