Benefit of patients with an early and progressed state of hepatocellular carcinoma treated with drug-eluting beads
Aim: To evaluate drug-eluting beads (DEB) for transarterial chemoembolization (TACE) in patients with Barcelona Clinic Liver Cancer (BCLC) A to D suffering from hepatocellular carcinoma. Material and Methods: The progression-free interval (PFI), survival and laboratory findings of 46 patients were r...
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| Hauptverfasser: | , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
September-October 2016
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| In: |
In vivo
Year: 2016, Jahrgang: 30, Heft: 5, Pages: 707-712 |
| ISSN: | 1791-7549 |
| Online-Zugang: | Verlag, Volltext: http://iv.iiarjournals.org/content/30/5/707
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| Verfasserangaben: | Nils Rathmann, Maliha Sadick, Bjoern Rathmann, Michael Kostrzewa, Christel Weiss, Stefan O. Schoenberg, Steffen J. Diehl and Christoph Antoni |
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| 245 | 1 | 0 | |a Benefit of patients with an early and progressed state of hepatocellular carcinoma treated with drug-eluting beads |c Nils Rathmann, Maliha Sadick, Bjoern Rathmann, Michael Kostrzewa, Christel Weiss, Stefan O. Schoenberg, Steffen J. Diehl and Christoph Antoni |
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| 520 | |a Aim: To evaluate drug-eluting beads (DEB) for transarterial chemoembolization (TACE) in patients with Barcelona Clinic Liver Cancer (BCLC) A to D suffering from hepatocellular carcinoma. Material and Methods: The progression-free interval (PFI), survival and laboratory findings of 46 patients were retrospectively analyzed after DEB TACE. Results: The mean survival interval was 16.93 months. The BCLC A/B group had significantly (p=0.01) longer survival compared to C/D: 20.44 and 10.36 months. Mean PFI was 10.75 months with a significantly (p=0.002) longer PFI of the BCLC A/B group (12.71 months) compared to BCLC C/D (3.91 months). In terms of possible adverse events (AEs) significant changes (p<0.05) were observed in cholinesterase, white blood cells, alkaline phosphatase and C-reactive protein. Conclusion: Mean survival and PFI results in the BCLC A/B patient group were comparable to historical controls. In addition, the results suggest that patients with BCLC stage C/D also benefited from DEB TACE. | ||
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