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T cell receptor-triggered nuclear actin network formation drives CD4+ T cell effector functions

T cell activation is regulated by numerous mechanisms upon T cell antigen receptor (TCR) engagement, including induction of specific cytokines by transcription factors like NF-κB and NFAT. Tsopoulidis et al. now show that TCR engagement causes rapid nuclear actin polymerization to create a dynamic a...

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Bibliographische Detailangaben
Hauptverfasser: Tsopoulidis, Nikolaos (VerfasserIn) , Kaw, Sheetal (VerfasserIn) , Laketa, Vibor (VerfasserIn) , Kutscheidt, Stefan (VerfasserIn) , Stolp-Rastätter, Bettina (VerfasserIn) , Fackler, Oliver Till (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 4 January 2019
In: Science immunology
Year: 2019, Jahrgang: 4, Heft: 31
ISSN:2470-9468
DOI:10.1126/sciimmunol.aav1987
Online-Zugang:Resolving-System, Volltext: http://dx.doi.org/10.1126/sciimmunol.aav1987
Verlag, Volltext: http://immunology.sciencemag.org/content/4/31/eaav1987
Volltext
Verfasserangaben:N. Tsopoulidis, S. Kaw, V. Laketa, S. Kutscheidt, C. Baarlink, B. Stolp, R. Grosse, O.T. Fackler

MARC

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