Super-resolved insights into human immunodeficiency virus biology
The recent development of fluorescence microscopy approaches overcoming the diffraction limit of light microscopy opened possibilities for studying small-scale cellular processes. The spatial resolution achieved by these novel techniques, together with the possibility to perform live-cell and multic...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
10 May 2016
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| In: |
FEBS letters
Year: 2016, Jahrgang: 590, Heft: 13, Pages: 1858-1876 |
| ISSN: | 1873-3468 |
| DOI: | 10.1002/1873-3468.12186 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1002/1873-3468.12186 Verlag, Volltext: https://febs.onlinelibrary.wiley.com/doi/abs/10.1002/1873-3468.12186 
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| Verfasserangaben: | Janina Hanne, Vojtech Zila, Mike Heilemann, Barbara Müller and Hans-Georg Kräusslich |
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| 520 | |a The recent development of fluorescence microscopy approaches overcoming the diffraction limit of light microscopy opened possibilities for studying small-scale cellular processes. The spatial resolution achieved by these novel techniques, together with the possibility to perform live-cell and multicolor imaging, make them ideally suited for visualization of native viruses and subviral structures within the complex environment of a host cell or organ, thus providing fundamentally new possibilities for investigating virus-cell interactions. Here, we review the use of super-resolution microscopy approaches to study virus-cell interactions, and discuss recent insights into human immunodeficiency virus biology obtained by exploiting these novel techniques. | ||
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