Decompressive hemicraniectomy in malignant middle cerebral artery infarction: the ‘real world' beyond studies
Background: Decompressive hemicraniectomy (DHC) is life-saving in patients with malignant middle cerebral artery infarction (MMI), but outcome, perspectives and complications after DHC in daily practice are largely unknown. Methods: From 2008 until 2014, we extracted patient's characteristics a...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 6, 2016
|
| In: |
European neurology
Year: 2016, Volume: 76, Issue: 1-2, Pages: 48-56 |
| ISSN: | 1421-9913 |
| DOI: | 10.1159/000446564 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1159/000446564 Verlag, Volltext: https://www-karger-com.ezproxy.medma.uni-heidelberg.de/Article/FullText/446564 
|
| Author Notes: | Hans-Werner Pledl, Carolin Hoyer, Juliane Rausch, Anne D. Ebert, Marcel Seiz, Mirko Arp, Michael G. Hennerici, Angelika Alonso |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1587632705 | ||
| 003 | DE-627 | ||
| 005 | 20230427034237.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190213s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1159/000446564 |2 doi | |
| 035 | |a (DE-627)1587632705 | ||
| 035 | |a (DE-576)517632705 | ||
| 035 | |a (DE-599)BSZ517632705 | ||
| 035 | |a (OCoLC)1341037930 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Pledl, Hans-Werner |d 1987- |e VerfasserIn |0 (DE-588)1115487450 |0 (DE-627)869815369 |0 (DE-576)477794491 |4 aut | |
| 245 | 1 | 0 | |a Decompressive hemicraniectomy in malignant middle cerebral artery infarction |b the ‘real world' beyond studies |c Hans-Werner Pledl, Carolin Hoyer, Juliane Rausch, Anne D. Ebert, Marcel Seiz, Mirko Arp, Michael G. Hennerici, Angelika Alonso |
| 264 | 1 | |c July 6, 2016 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 13.02.2019 | ||
| 520 | |a Background: Decompressive hemicraniectomy (DHC) is life-saving in patients with malignant middle cerebral artery infarction (MMI), but outcome, perspectives and complications after DHC in daily practice are largely unknown. Methods: From 2008 until 2014, we extracted patient's characteristics as well as complications from our database for patients with MMI who underwent DHC. Additionally, we analysed medical records from the different rehabilitation steps. Results: We identified 48 consecutive patients (mean 57 years, 21 male, 41.7% >60 years) with MMI who underwent DHC. The decision for DHC was made on an individual basis, including patients without impaired consciousness or stroke onset >48 h. In-hospital patients achieved only marginal clinical improvement. Seventy-five percent attended an early-rehabilitation, 44% achieved post-stroke rehabilitation and 6% carried on late-stage rehabilitation. In all, 45.5% returned home after rehabilitation. In-hospital mortality was 14.6%, overall mortality was 16.7%. Surviving patients (78.9%) had a modified Rankin Scale of 4-5. Frequent neurologic complications were symptomatic epilepsy and delirium. Following DHC/bone-flap-reimplantation, wound-healing disorders, epidural hematoma and wound infections were major surgery-related complications. Pulmonary infections were frequent in the acute-phase and urinary tract infections were predominant in the late-phase. Conclusions: DHC is a life-saving technique in patients with MMI, but complications are frequent, were underestimated in randomized clinical trials and may worsen the functional outcome. | ||
| 700 | 1 | |a Hoyer, Carolin |d 1976- |e VerfasserIn |0 (DE-588)136673562 |0 (DE-627)694568090 |0 (DE-576)301202133 |4 aut | |
| 700 | 1 | |a Ebert, Anne |d 1971- |e VerfasserIn |0 (DE-588)122028635 |0 (DE-627)081691998 |0 (DE-576)175098344 |4 aut | |
| 700 | 1 | |a Seiz-Rosenhagen, Marcel |d 1977- |e VerfasserIn |0 (DE-588)129921807 |0 (DE-627)483655503 |0 (DE-576)297904019 |4 aut | |
| 700 | 1 | |a Arp, Mirko |d 1977- |e VerfasserIn |0 (DE-588)1017764301 |0 (DE-627)679258043 |0 (DE-576)354307401 |4 aut | |
| 700 | 1 | |a Hennerici, Michael G. |d 1948- |e VerfasserIn |0 (DE-588)11587545X |0 (DE-627)077527704 |0 (DE-576)290126444 |4 aut | |
| 700 | 1 | |a Alonso, Angelika |d 1977- |e VerfasserIn |0 (DE-588)1025166795 |0 (DE-627)721355315 |0 (DE-576)370025865 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European neurology |d Basel : Karger, 1968 |g 76(2016), 1-2, Seite 48-56 |h Online-Ressource |w (DE-627)300191448 |w (DE-600)1482237-4 |w (DE-576)273865196 |x 1421-9913 |7 nnas |a Decompressive hemicraniectomy in malignant middle cerebral artery infarction the ‘real world' beyond studies |
| 773 | 1 | 8 | |g volume:76 |g year:2016 |g number:1-2 |g pages:48-56 |g extent:9 |a Decompressive hemicraniectomy in malignant middle cerebral artery infarction the ‘real world' beyond studies |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1159/000446564 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://www-karger-com.ezproxy.medma.uni-heidelberg.de/Article/FullText/446564 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190213 | ||
| 993 | |a Article | ||
| 994 | |a 2016 | ||
| 998 | |g 1025166795 |a Alonso, Angelika |m 1025166795:Alonso, Angelika |d 60000 |d 62700 |e 60000PA1025166795 |e 62700PA1025166795 |k 0/60000/ |k 1/60000/62700/ |p 8 |y j | ||
| 998 | |g 11587545X |a Hennerici, Michael G. |m 11587545X:Hennerici, Michael G. |d 60000 |d 62700 |e 60000PH11587545X |e 62700PH11587545X |k 0/60000/ |k 1/60000/62700/ |p 7 | ||
| 998 | |g 1017764301 |a Arp, Mirko |m 1017764301:Arp, Mirko |d 60000 |d 62600 |e 60000PA1017764301 |e 62600PA1017764301 |k 0/60000/ |k 1/60000/62600/ |p 6 | ||
| 998 | |g 129921807 |a Seiz-Rosenhagen, Marcel |m 129921807:Seiz-Rosenhagen, Marcel |d 60000 |d 62600 |e 60000PS129921807 |e 62600PS129921807 |k 0/60000/ |k 1/60000/62600/ |p 5 | ||
| 998 | |g 122028635 |a Ebert, Anne |m 122028635:Ebert, Anne |d 60000 |d 62700 |e 60000PE122028635 |e 62700PE122028635 |k 0/60000/ |k 1/60000/62700/ |p 4 | ||
| 998 | |g 136673562 |a Hoyer, Carolin |m 136673562:Hoyer, Carolin |d 60000 |d 62700 |e 60000PH136673562 |e 62700PH136673562 |k 0/60000/ |k 1/60000/62700/ |p 2 | ||
| 999 | |a KXP-PPN1587632705 |e 3055870786 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 13.02.2019"],"recId":"1587632705","physDesc":[{"extent":"9 S."}],"name":{"displayForm":["Hans-Werner Pledl, Carolin Hoyer, Juliane Rausch, Anne D. Ebert, Marcel Seiz, Mirko Arp, Michael G. Hennerici, Angelika Alonso"]},"id":{"doi":["10.1159/000446564"],"eki":["1587632705"]},"origin":[{"dateIssuedKey":"2016","dateIssuedDisp":"July 6, 2016"}],"relHost":[{"id":{"eki":["300191448"],"zdb":["1482237-4"],"issn":["1421-9913"]},"type":{"bibl":"periodical","media":"Online-Ressource"},"pubHistory":["1.1968 -"],"note":["Gesehen am 25.04.2019"],"recId":"300191448","part":{"pages":"48-56","extent":"9","year":"2016","text":"76(2016), 1-2, Seite 48-56","issue":"1-2","volume":"76"},"language":["eng"],"disp":"Decompressive hemicraniectomy in malignant middle cerebral artery infarction the ‘real world' beyond studiesEuropean neurology","physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisherPlace":"Basel","dateIssuedKey":"1968","publisher":"Karger","dateIssuedDisp":"1968-"}],"title":[{"title":"European neurology","title_sort":"European neurology"}]}],"person":[{"roleDisplay":"VerfasserIn","role":"aut","given":"Hans-Werner","display":"Pledl, Hans-Werner","family":"Pledl"},{"display":"Hoyer, Carolin","role":"aut","roleDisplay":"VerfasserIn","given":"Carolin","family":"Hoyer"},{"display":"Ebert, Anne","given":"Anne","roleDisplay":"VerfasserIn","role":"aut","family":"Ebert"},{"family":"Seiz-Rosenhagen","display":"Seiz-Rosenhagen, Marcel","roleDisplay":"VerfasserIn","role":"aut","given":"Marcel"},{"family":"Arp","display":"Arp, Mirko","role":"aut","roleDisplay":"VerfasserIn","given":"Mirko"},{"family":"Hennerici","display":"Hennerici, Michael G.","given":"Michael G.","role":"aut","roleDisplay":"VerfasserIn"},{"family":"Alonso","roleDisplay":"VerfasserIn","role":"aut","given":"Angelika","display":"Alonso, Angelika"}],"language":["eng"],"title":[{"title_sort":"Decompressive hemicraniectomy in malignant middle cerebral artery infarction","title":"Decompressive hemicraniectomy in malignant middle cerebral artery infarction","subtitle":"the ‘real world' beyond studies"}]} | ||
| SRT | |a PLEDLHANSWDECOMPRESS6201 | ||