Central corneal thickness in spectral-domain OCT and associations with ocular and systemic parameters
Background. Optical coherence tomography (OCT) allows quantitative analysis of the anterior segment of the eye with a noncontact examination. The aim of this study is to analyze associations of central corneal thickness (CCT) as measured by OCT with ocular and systemic cardiovascular parameters. Met...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2016
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| In: |
Journal of ophthalmology
Year: 2016, Pages: 1-6 |
| ISSN: | 2090-0058 |
| DOI: | 10.1155/2016/2596956 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1155/2016/2596956 Verlag, Volltext: https://www.hindawi.com/journals/joph/2016/2596956/ 
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| Author Notes: | Alexander Karl-Georg Schuster, Joachim Ernst Fischer, and Urs Vossmerbaeumer |
| Summary: | Background. Optical coherence tomography (OCT) allows quantitative analysis of the anterior segment of the eye with a noncontact examination. The aim of this study is to analyze associations of central corneal thickness (CCT) as measured by OCT with ocular and systemic cardiovascular parameters. Methods. A cross-sectional study of 734 persons was performed in a working age population. Only healthy eyes were included. A comprehensive ophthalmological examination including refraction, noncontact tonometry, and imaging of the anterior segment by SD-OCT was performed. In parallel, a broad range of systemic cardiovascular parameters were measured. Associations were analyzed using a generalized estimating equations’ model. Results. CCT measurements showed a significant association with corneal curvature and intraocular pressure: a thinner CCT was associated with a flatter cornea and with lower intraocular pressure (). Age was positively associated with CCT (); all other cardiovascular parameters were not associated. Conclusion. A thinner cornea is associated with a flatter surface and with lower intraocular pressure readings, while there are no independent associations with refraction and systemic cardiovascular parameters. Our findings highlight the value of SD-OCT CCT measurements as a standard tool in anterior segment analysis. |
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| Item Description: | Gesehen am 19.02.2019 |
| Physical Description: | Online Resource |
| ISSN: | 2090-0058 |
| DOI: | 10.1155/2016/2596956 |