Cisplatin-based chemotherapy for testicular germ cell tumors: complication rates of peripheral versus central venous administration
Objective: Despite the low local toxicity of the used agents, Cisplatin-based chemotherapy (CBP) for patients with testicular germ cell tumors (TGCT) is mostly delivered via a central venous access (CVA). Since 2008, CBP is given peripherally in our hospital. Methods: Medical reports of TGCT patient...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
February 2016
|
| In: |
Urologia internationalis
Year: 2016, Volume: 96, Issue: 2, Pages: 177-182 |
| ISSN: | 1423-0399 |
| DOI: | 10.1159/000442003 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1159/000442003 Verlag, Volltext: https://www-karger-com.ezproxy.medma.uni-heidelberg.de/Article/FullText/442003 
|
| Author Notes: | Thomas Worst, Lisa Sautter, Axel John, Christel Weiss, Axel Häcker, Julia Heinzelbecker |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1588126846 | ||
| 003 | DE-627 | ||
| 005 | 20220815112325.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190226s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1159/000442003 |2 doi | |
| 035 | |a (DE-627)1588126846 | ||
| 035 | |a (DE-576)518126846 | ||
| 035 | |a (DE-599)BSZ518126846 | ||
| 035 | |a (OCoLC)1341040218 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Worst, Thomas |d 1985- |e VerfasserIn |0 (DE-588)1028335679 |0 (DE-627)73058500X |0 (DE-576)375827501 |4 aut | |
| 245 | 1 | 0 | |a Cisplatin-based chemotherapy for testicular germ cell tumors |b complication rates of peripheral versus central venous administration |c Thomas Worst, Lisa Sautter, Axel John, Christel Weiss, Axel Häcker, Julia Heinzelbecker |
| 264 | 1 | |c February 2016 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 26.02.2019 | ||
| 500 | |a Published online: December 18, 2015 | ||
| 520 | |a Objective: Despite the low local toxicity of the used agents, Cisplatin-based chemotherapy (CBP) for patients with testicular germ cell tumors (TGCT) is mostly delivered via a central venous access (CVA). Since 2008, CBP is given peripherally in our hospital. Methods: Medical reports of TGCT patients who received CBP between September 1991 and August 2014 were evaluated. Complications regarding the way of administration (CVA vs. peripheral venous catheter [PVC]) were classified according to the Common Terminology Criteria of Adverse Events. The complication rates were compared using chi square test and propensity score matching. Results: During 288 cycles in 109 patients, 85 complications (29.5%) were observed with similar rates for overall (PVC 31.3%, CVA 29.9%; p = 0.820) and grade I complications (21.3%, 25.4%; p = 0.470). More grade II complications were observed in the PVC group (10.0 vs. 1.5%; p < 0.001). Grade III complications requiring invasive treatment were found only in the CVA group (3.0%; p = 0.120). Using propensity score matching, no differences in overall (p = 0.950), grade I (p = 0.540) and grades II/III (p = 0.590) complications were seen. Conclusion: The peripheral and central administration of CBP has similar overall complication rates. Despite more grade II complications, the peripheral administration of CBP is a safe alternative for TGCT patients. Additionally, no severe grade III complications occurred. | ||
| 700 | 1 | |a Sautter, Lisa |d 1988- |e VerfasserIn |0 (DE-588)1162086785 |0 (DE-627)1025519132 |0 (DE-576)507095014 |4 aut | |
| 700 | 1 | |a Weiß, Christel |d 1958- |e VerfasserIn |0 (DE-588)123287707 |0 (DE-627)082463417 |0 (DE-576)168356104 |4 aut | |
| 700 | 1 | |a Häcker, Axel |d 1971- |e VerfasserIn |0 (DE-588)121732177 |0 (DE-627)705632865 |0 (DE-576)292855923 |4 aut | |
| 700 | 1 | |a Heinzelbecker, Julia |d 1980- |e VerfasserIn |0 (DE-588)137812159 |0 (DE-627)596128185 |0 (DE-576)304666467 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Urologia internationalis |d Basel : Karger, 1955 |g 96(2016), 2, Seite 177-182 |h Online-Ressource |w (DE-627)265510333 |w (DE-600)1464417-4 |w (DE-576)276270991 |x 1423-0399 |7 nnas |a Cisplatin-based chemotherapy for testicular germ cell tumors complication rates of peripheral versus central venous administration |
| 773 | 1 | 8 | |g volume:96 |g year:2016 |g number:2 |g pages:177-182 |g extent:6 |a Cisplatin-based chemotherapy for testicular germ cell tumors complication rates of peripheral versus central venous administration |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1159/000442003 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://www-karger-com.ezproxy.medma.uni-heidelberg.de/Article/FullText/442003 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190226 | ||
| 993 | |a Article | ||
| 994 | |a 2016 | ||
| 998 | |g 137812159 |a Heinzelbecker, Julia |m 137812159:Heinzelbecker, Julia |d 60000 |d 63100 |e 60000PH137812159 |e 63100PH137812159 |k 0/60000/ |k 1/60000/63100/ |p 6 |y j | ||
| 998 | |g 121732177 |a Häcker, Axel |m 121732177:Häcker, Axel |d 60000 |d 63100 |e 60000PH121732177 |e 63100PH121732177 |k 0/60000/ |k 1/60000/63100/ |p 5 | ||
| 998 | |g 123287707 |a Weiß, Christel |m 123287707:Weiß, Christel |d 60000 |d 60200 |d 60250 |e 60000PW123287707 |e 60200PW123287707 |e 60250PW123287707 |k 0/60000/ |k 1/60000/60200/ |k 2/60000/60200/60250/ |p 4 | ||
| 998 | |g 1162086785 |a Sautter, Lisa |m 1162086785:Sautter, Lisa |d 60000 |d 63000 |e 60000PS1162086785 |e 63000PS1162086785 |k 0/60000/ |k 1/60000/63000/ |p 2 | ||
| 998 | |g 1028335679 |a Worst, Thomas |m 1028335679:Worst, Thomas |d 60000 |d 63100 |e 60000PW1028335679 |e 63100PW1028335679 |k 0/60000/ |k 1/60000/63100/ |p 1 |x j | ||
| 999 | |a KXP-PPN1588126846 |e 3056763703 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1588126846","name":{"displayForm":["Thomas Worst, Lisa Sautter, Axel John, Christel Weiss, Axel Häcker, Julia Heinzelbecker"]},"type":{"bibl":"article-journal","media":"Online-Ressource"},"language":["eng"],"id":{"doi":["10.1159/000442003"],"eki":["1588126846"]},"note":["Gesehen am 26.02.2019","Published online: December 18, 2015"],"origin":[{"dateIssuedDisp":"February 2016","dateIssuedKey":"2016"}],"relHost":[{"id":{"eki":["265510333"],"issn":["1423-0399"],"zdb":["1464417-4"]},"pubHistory":["1.1955 -"],"recId":"265510333","physDesc":[{"extent":"Online-Ressource"}],"note":["Gesehen am 13.04.2021"],"origin":[{"publisherPlace":"Basel","dateIssuedKey":"1955","publisher":"Karger","dateIssuedDisp":"1955-"}],"disp":"Cisplatin-based chemotherapy for testicular germ cell tumors complication rates of peripheral versus central venous administrationUrologia internationalis","type":{"media":"Online-Ressource","bibl":"periodical"},"language":["ger"],"title":[{"subtitle":"an independent international forum for clinically oriented research","title":"Urologia internationalis","title_sort":"Urologia internationalis"}],"part":{"extent":"6","year":"2016","volume":"96","issue":"2","pages":"177-182","text":"96(2016), 2, Seite 177-182"}}],"person":[{"display":"Worst, Thomas","role":"aut","given":"Thomas","family":"Worst"},{"given":"Lisa","family":"Sautter","role":"aut","display":"Sautter, Lisa"},{"display":"Weiß, Christel","role":"aut","given":"Christel","family":"Weiß"},{"display":"Häcker, Axel","role":"aut","given":"Axel","family":"Häcker"},{"role":"aut","display":"Heinzelbecker, Julia","family":"Heinzelbecker","given":"Julia"}],"title":[{"subtitle":"complication rates of peripheral versus central venous administration","title_sort":"Cisplatin-based chemotherapy for testicular germ cell tumors","title":"Cisplatin-based chemotherapy for testicular germ cell tumors"}],"physDesc":[{"extent":"6 S."}]} | ||
| SRT | |a WORSTTHOMACISPLATINB2016 | ||