Changes in baroreceptor sensitivity after eversion carotid endarterectomy
Objective: Posteversion carotid endarterectomy hypertension has been suggested to be associated with impaired baroreceptor sensitivity (BRS), which has been identified as a factor of prognostic relevance in patients with cardiovascular disease. The aim of this prospective single-center nonrandomized...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
27 March 2012
|
| In: |
Journal of vascular surgery
Year: 2012, Jahrgang: 55, Heft: 5, Pages: 1322-1328 |
| ISSN: | 1097-6809 |
| DOI: | 10.1016/j.jvs.2011.11.134 |
| Online-Zugang: | Verlag, Volltext: http://dx.doi.org/10.1016/j.jvs.2011.11.134 Verlag, Volltext: https://linkinghub.elsevier.com/retrieve/pii/S0741521411029612 
|
| Verfasserangaben: | Serdar Demirel, Nicolas Attigah, Hans Bruijnen, Laura Macek, Maani Hakimi, Thomas Able and Dittmar Böckler |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1588134768 | ||
| 003 | DE-627 | ||
| 005 | 20220815112446.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190226s2012 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.jvs.2011.11.134 |2 doi | |
| 035 | |a (DE-627)1588134768 | ||
| 035 | |a (DE-576)518134768 | ||
| 035 | |a (DE-599)BSZ518134768 | ||
| 035 | |a (OCoLC)1341040160 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Demirel, Serdar |d 1977- |e VerfasserIn |0 (DE-588)130655481 |0 (DE-627)505290936 |0 (DE-576)298324970 |4 aut | |
| 245 | 1 | 0 | |a Changes in baroreceptor sensitivity after eversion carotid endarterectomy |c Serdar Demirel, Nicolas Attigah, Hans Bruijnen, Laura Macek, Maani Hakimi, Thomas Able and Dittmar Böckler |
| 264 | 1 | |c 27 March 2012 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 26.02.2019 | ||
| 520 | |a Objective: Posteversion carotid endarterectomy hypertension has been suggested to be associated with impaired baroreceptor sensitivity (BRS), which has been identified as a factor of prognostic relevance in patients with cardiovascular disease. The aim of this prospective single-center nonrandomized study was to describe the changes of BRS in the early postoperative period after eversion carotid endarterectomy (E-CEA). Methods: Spontaneous BRS and hemodynamic parameters such as blood pressure (BP), heart rate (HR), cardiac output (CO), and total peripheral resistance (TPR) were evaluated preoperatively as well as postoperatively after 1 and 3 days using a noninvasive sequential cross-correlation method. Additionally, any modification in vasoactive medication due to BP derangement in the postoperative period was noted. Due to non-normal distribution of BRS, HR, and TPR samples, all measured values were expressed as medians with interquartile range (IQR), and a nonparametric test (Friedman) was performed. After adjustment for multiple testing, differences were considered statistically significant when the two-tailed P value was less than .0036. Results: Thirty-five patients (mean age, 71 years) with symptomatic or asymptomatic internal carotid artery stenosis were included. The BRS significantly decreased to a lower level 24 hours after surgery (4.71 ms/mm Hg [3.02-6.1]) than preoperatively (5.95 ms/mm Hg [4.68-10.86]; P < .0001), resulting in a within-patient difference of -2.46 ms/mm Hg (95% confidence interval [CI], - 8.38 - -1.52). This difference (95% CI, [- 1.58 (- 8.24 - - 0.80)]) persisted at the 72-hour measurements (5.63 ms/mm Hg [3.23-7.69]; P ؍ .0005). The HR, reflecting the sympathetic activity, increased 24 hours after the operation (69 bpm [61.3-77.7]) compared with preoperative values (63 bpm [57.9-73.2]; P ؍ .005) (within-patient difference [95% CI] 3.7 [1.5-8.5]), and this increase reached significance at 72 hours (69 bpm [65.4-77.5]; P ؍ .001) (within-patient difference [95% CI] 5.5 [2.3-8.8]). Values of systolic pressure, diastolic pressure, mean arterial pressure, CO, and TPR were not significantly different between pre- and postoperative measurements. Overall, 23 (66%) patients developed significant postoperative hypertension requiring aggressive management with additional medications. Conclusions: E-CEA might have a decreasing influence on BRS, leading to increased sympathetic activity. Investigations of the longer-term effects of impaired BRS are warranted. These findings should be interpreted with caution, noting the limitation of an absent control group. ( J Vasc Surg 2012;55:1322-8.) | ||
| 700 | 1 | |a Attigah, Nicolas |d 1968- |e VerfasserIn |0 (DE-588)124224903 |0 (DE-627)085720143 |0 (DE-576)185827721 |4 aut | |
| 700 | 1 | |a Macek, Laura |d 1984- |e VerfasserIn |0 (DE-588)1052151841 |0 (DE-627)787928119 |0 (DE-576)407908676 |4 aut | |
| 700 | 1 | |a Hakimi, Maani |d 1972- |e VerfasserIn |0 (DE-588)130842494 |0 (DE-627)506359727 |0 (DE-576)298370891 |4 aut | |
| 700 | 1 | |a Able, Thomas |d 1967- |e VerfasserIn |0 (DE-588)143505688 |0 (DE-627)646582127 |0 (DE-576)337427461 |4 aut | |
| 700 | 1 | |a Böckler, Dittmar |d 1966- |e VerfasserIn |0 (DE-588)1032367881 |0 (DE-627)738382868 |0 (DE-576)173503969 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of vascular surgery |d Amsterdam [u.a.] : Elsevier, 1984 |g 55(2012), 5, Seite 1322-1328 |h Online-Ressource |w (DE-627)302720146 |w (DE-600)1492043-8 |w (DE-576)088704807 |x 1097-6809 |7 nnas |a Changes in baroreceptor sensitivity after eversion carotid endarterectomy |
| 773 | 1 | 8 | |g volume:55 |g year:2012 |g number:5 |g pages:1322-1328 |g extent:7 |a Changes in baroreceptor sensitivity after eversion carotid endarterectomy |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.jvs.2011.11.134 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://linkinghub.elsevier.com/retrieve/pii/S0741521411029612 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190226 | ||
| 993 | |a Article | ||
| 994 | |a 2012 | ||
| 998 | |g 143505688 |a Able, Thomas |m 143505688:Able, Thomas |d 910000 |d 910200 |e 910000PA143505688 |e 910200PA143505688 |k 0/910000/ |k 1/910000/910200/ | ||
| 998 | |g 1032367881 |a Böckler, Dittmar |m 1032367881:Böckler, Dittmar |d 910000 |d 910200 |e 910000PB1032367881 |e 910200PB1032367881 |k 0/910000/ |k 1/910000/910200/ | ||
| 998 | |g 130842494 |a Hakimi, Maani |m 130842494:Hakimi, Maani |d 910000 |d 910200 |e 910000PH130842494 |e 910200PH130842494 |k 0/910000/ |k 1/910000/910200/ | ||
| 998 | |g 1052151841 |a Macek, Laura |m 1052151841:Macek, Laura |d 910000 |d 910200 |e 910000PM1052151841 |e 910200PM1052151841 |k 0/910000/ |k 1/910000/910200/ | ||
| 998 | |g 124224903 |a Attigah, Nicolas |m 124224903:Attigah, Nicolas |d 910000 |d 910200 |e 910000PA124224903 |e 910200PA124224903 |k 0/910000/ |k 1/910000/910200/ | ||
| 998 | |g 130655481 |a Demirel, Serdar |m 130655481:Demirel, Serdar |d 910000 |d 910200 |e 910000PD130655481 |e 910200PD130655481 |k 0/910000/ |k 1/910000/910200/ |p 1 |x j | ||
| 999 | |a KXP-PPN1588134768 |e 3056777704 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"recId":"1588134768","person":[{"role":"aut","family":"Demirel","display":"Demirel, Serdar","given":"Serdar"},{"display":"Attigah, Nicolas","given":"Nicolas","family":"Attigah","role":"aut"},{"given":"Laura","display":"Macek, Laura","role":"aut","family":"Macek"},{"role":"aut","family":"Hakimi","display":"Hakimi, Maani","given":"Maani"},{"family":"Able","role":"aut","display":"Able, Thomas","given":"Thomas"},{"family":"Böckler","role":"aut","display":"Böckler, Dittmar","given":"Dittmar"}],"note":["Gesehen am 26.02.2019"],"name":{"displayForm":["Serdar Demirel, Nicolas Attigah, Hans Bruijnen, Laura Macek, Maani Hakimi, Thomas Able and Dittmar Böckler"]},"language":["eng"],"relHost":[{"language":["eng"],"part":{"year":"2012","volume":"55","text":"55(2012), 5, Seite 1322-1328","pages":"1322-1328","extent":"7","issue":"5"},"note":["Gesehen am 15.01.20"],"pubHistory":["1.1984 -"],"disp":"Changes in baroreceptor sensitivity after eversion carotid endarterectomyJournal of vascular surgery","type":{"media":"Online-Ressource","bibl":"periodical"},"titleAlt":[{"title":"JVS"},{"title":"Vascular surgery"}],"recId":"302720146","title":[{"title":"Journal of vascular surgery","title_sort":"Journal of vascular surgery"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"zdb":["1492043-8"],"issn":["1097-6809"],"eki":["302720146"]},"origin":[{"publisher":"Elsevier ; Mosby","dateIssuedDisp":"1984-","dateIssuedKey":"1984","publisherPlace":"Amsterdam [u.a.] ; St. Louis, Mo."}]}],"origin":[{"dateIssuedKey":"2012","dateIssuedDisp":"27 March 2012"}],"title":[{"title_sort":"Changes in baroreceptor sensitivity after eversion carotid endarterectomy","title":"Changes in baroreceptor sensitivity after eversion carotid endarterectomy"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"physDesc":[{"extent":"7 S."}],"id":{"eki":["1588134768"],"doi":["10.1016/j.jvs.2011.11.134"]}} | ||
| SRT | |a DEMIRELSERCHANGESINB2720 | ||