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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

GWAS have identified more than 500 genetic loci associated with blood lipid levels. Here, the authors report a genome-wide analysis of interactions between genetic markers and physical activity, and find that physical activity modifies the effects of four genetic loci on HDL or LDL cholesterol.

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Bibliographische Detailangaben
Hauptverfasser: Kilpeläinen, Tuomas O. (VerfasserIn) , Jonas, Jost B. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 22 January 2019
In: Nature Communications
Year: 2019, Jahrgang: 10
ISSN:2041-1723
DOI:10.1038/s41467-018-08008-w
Online-Zugang:Verlag, Volltext: http://dx.doi.org/10.1038/s41467-018-08008-w
Verlag, Volltext: https://www.nature.com/articles/s41467-018-08008-w
Volltext
Verfasserangaben:Tuomas O. Kilpeläinen et al.#
Beschreibung
Zusammenfassung:GWAS have identified more than 500 genetic loci associated with blood lipid levels. Here, the authors report a genome-wide analysis of interactions between genetic markers and physical activity, and find that physical activity modifies the effects of four genetic loci on HDL or LDL cholesterol.
Beschreibung:#Tuomas O. Kilpeläinen, Jost B. Jonas [und weitere]
Gesehen am 04.03.2019
Beschreibung:Online Resource
ISSN:2041-1723
DOI:10.1038/s41467-018-08008-w

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