Inhibitory Regulation of Excitatory Neurotransmission

Within the central and peripheral nervous systems of animals, including man, inhibition is crucial to counterbalance excitatory neurotransmission, which is predominantly mediated by glutamate and its receptors. Although, particularly in brain, much of this inhibition is provided by classical post-sy...

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Bibliographische Detailangaben
Weitere Verfasser: Darlison, Mark G. (BerichterstatterIn)
Dokumenttyp: Sammelband
Sprache:Englisch
Veröffentlicht: Berlin, Heidelberg Springer-Verlag Berlin Heidelberg 2008
Schriftenreihe:Results and Problems in Cell Differentiation 44
SpringerLink Bücher
Volumes / Articles: Show Volumes / Articles.
DOI:10.1007/978-3-540-72602-9
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Online-Zugang:Verlag, Volltext: https://doi.org/10.1007/978-3-540-72602-9
Resolving-System, lizenzpflichtig, Volltext: http://dx.doi.org/10.1007/978-3-540-72602-9
Cover: https://swbplus.bsz-bw.de/bsz273087231cov.jpg
Volltext
Verfasserangaben:edited by Mark G. Darlison
Beschreibung
Zusammenfassung:Within the central and peripheral nervous systems of animals, including man, inhibition is crucial to counterbalance excitatory neurotransmission, which is predominantly mediated by glutamate and its receptors. Although, particularly in brain, much of this inhibition is provided by classical post-synaptic GABAA receptors, many other proteins and mechanisms regulate excitation. These exist both to "fine tune" neurotransmission and to prevent overexcitation that could lead to conditions such as epilepsy and excitotoxicity, which can result in cell death.This book reviews aspects of GAB
Beschreibung:Description based upon print version of record
Beschreibung:Online Resource
ISBN:9783540726029
DOI:10.1007/978-3-540-72602-9