Respiratory Regulation - The Molecular Approach
This book, an international collaborative effort in the area of molecular respiratory research, showcases a broad range of multidisciplinary approaches to unravel and analyze the underlying mechanisms of a spectrum of respiratory ailments. It discusses immunological and genetic respiratory disorders...
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| 1. Verfasser: | |
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| Dokumenttyp: | Buch/Monographie |
| Sprache: | Englisch |
| Veröffentlicht: |
Dordrecht
Springer
2013
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| Schriftenreihe: | Advances in experimental medicine and biology
756 |
| In: |
Advances in experimental medicine and biology (756)
|
| Volumes / Articles: | Show Volumes / Articles. |
| DOI: | 10.1007/978-94-007-4549-0 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1007/978-94-007-4549-0 Resolving-System, lizenzpflichtig, Volltext: http://dx.doi.org/10.1007/978-94-007-4549-0 Cover: https://swbplus.bsz-bw.de/bsz373364709cov.jpg 
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| Verfasserangaben: | edited by Mieczyslaw Pokorski |
MARC
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| 505 | 8 | |a Respiratory Regulation -The Molecular Approach; Preface; Contents; Chapter 1: Neutrophil Extracellular Trap in Human Diseases; 1.1 Introduction; 1.2 Characterization of Neutrophil Extracellular Traps; 1.3 NETs in Neoplasm of Developmental Age; 1.4 NETs in Autoimmunity; References; Chapter 2: Tiotropium Increases PPARγ and Decreases CREB in Cells Isolated from Induced Sputum of COPD Patients; 2.1 Introduction; 2.2 Methods; 2.2.1 Subjects and Treatment; 2.2.2 Sputum Induction and Processing; 2.3 Results; 2.4 Discussion; References | |
| 505 | 8 | |a Chapter 3: Expression of Ki-67, Bcl-2, Survivin and p53 Proteins in Patients with Pulmonary Carcinoma3.1 Introduction; 3.2 Methods; 3.2.1 Evaluation of Immunochemical Staining; 3.2.2 Statistical Analysis; 3.3 Results; 3.4 Discussion; References; Chapter 4: Indacaterol Add-On Therapy Improves Lung Function, Exercise Capacity and Life Quality of COPD Patients; 4.1 Introduction; 4.2 Methods; 4.3 Results; 4.4 Discussion; References; Chapter 5: Rapid DNA Extraction Protocol for Detection of Alpha-1 Antitrypsin Deficiency from Dried Blood Spots by Real-Time PCR; 5.1 Introduction; 5.2 Methods | |
| 505 | 8 | |a 5.2.1 Preparation of DBS Samples5.2.2 DNA Extraction from DBS; 5.2.3 Genotyping of PI*S and PI*Z AAT Alleles by Real-Time PCR; 5.2.4 AAT Sequence Analysis; 5.2.5 Quantitative Determination of Serum AAT Concentration by Immune Nephelometry; 5.2.6 Phenotyping of Serum AAT by Isoelectrofocusing (IEF); 5.3 Results; 5.4 Discussion; References; Chapter 6: CRAC Ion Channels and Airway Defense Reflexes in Experimental Allergic Inflammation; 6.1 Introduction; 6.2 Methods; 6.2.1 Animals; 6.2.2 Antigen-Induced Airway Hyperresponsiveness; 6.2.3 Chemicals | |
| 505 | 8 | |a 6.2.4 Evaluation of Airway Smooth Muscle (ASM) Reactivity In Vivo6.2.5 Cough Reflex Assessment; 6.2.6 Evaluation of Airway Smooth Muscle (ASM) Reactivity In Vivo; 6.2.7 Measurement of Exhaled NO (E NO); 6.2.8 Histological Evaluation; 6.2.9 Statistical Analysis; 6.3 Results; 6.3.1 Airways Smooth Muscle Reactivity In Vivo; 6.3.2 Airway Smooth Muscle Reactivity In Vitro; 6.3.3 Exhaled NO Changes; 6.3.4 Citric Acid-Induced Cough Reflex; 6.3.5 Histological Results; 6.4 Discussion; References; Chapter 7: Experimental Model of Allergic Asthma; 7.1 Introduction; 7.2 Methods | |
| 505 | 8 | |a 7.2.1 Sensitization of Guinea Pigs7.2.2 Tracheal Smooth Muscle Contraction in vitro; 7.2.3 Evaluation of Airway Reactivity in vivo; 7.2.4 Chemically Induced Cough; 7.2.5 Measurement of In fl ammatory Cytokines; 7.2.6 Histological Examination; 7.2.7 Data Analysis; 7.3 Results; 7.4 Discussion; References; Chapter 8: Effects of Selective Inhibition of PDE4 and PDE7 on Airway Reactivity and Cough in Healthy and Ovalbumin-Sensitized Guinea Pigs; 8.1 Introduction; 8.2 Methods; 8.2.1 Antigen-Induced Airway Hyperresponsiveness; 8.2.2 Cough Reflex Assessment | |
| 505 | 8 | |a 8.2.3 Evaluation of Airway Reactivity In Vivo | |
| 520 | |a This book, an international collaborative effort in the area of molecular respiratory research, showcases a broad range of multidisciplinary approaches to unravel and analyze the underlying mechanisms of a spectrum of respiratory ailments. It discusses immunological and genetic respiratory disorders, cancer, respiratory allergies and cough, sleep disordered breathing and many others. Exciting new results and up-to-date critical overviews of widely debated topics pertaining to respiratory disorders are presented. The contributions provide evidence for the growing interest of the international community of researchers in the field of respiration. The book incorporates modern molecular approaches to diagnostic and treatment solutions, underscoring the need for rational, evidence-based treatment methods. Combining cutting edge basic and clinical research with expert knowledge and experience this book is essential reading for medical students, research scientists and practicing specialists in pulmonology, immunology and allergology. | ||
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| 650 | 0 | |a Pneumology | |
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