Pre-analytics of pathological specimens in oncology
This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pat...
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| Other Authors: | , , , |
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| Format: | Book/Monograph |
| Language: | English |
| Published: |
Cham s.l.
Springer International Publishing Imprint: Springer
2015
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| Series: | Recent results in cancer research
199 |
| In: |
Recent results in cancer research (199)
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| Volumes / Articles: | Show Volumes / Articles. |
| DOI: | 10.1007/978-3-319-13957-9 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1007/978-3-319-13957-9 Resolving-System, lizenzpflichtig, Volltext: http://dx.doi.org/10.1007/978-3-319-13957-9 Cover: https://swbplus.bsz-bw.de/bsz425836045cov.jpg 
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| Author Notes: | edited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz Winterfeld |
MARC
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| 505 | 8 | |a What Is Pre-Analytics in Surgical Pathology? Histologic Validation of Vacuum Sealed Formalin -- Free Tissue Preservation and Transport System -- Pre-Analytics and Molecular Pathology -- Experiences in Vacuum Preparation of Routine Specimens -- Tissue Heterogeneity as a Pre-Analytical Source of Variability -- Vacuum Fixation of Breast Specimens Before Grossing -- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing? -- Current Projects in Pre-Analytics - Where to Go? -- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications -- Experiences With Pre-Analytics of Lung Specimen -- Experiences With Pre-Analytics of GI-Specimen -- Bone Marrow Work-Up -- Two-Temperature Fixation Preserves Activation Status with High Efficiency -- Towards the Lean Lab. The Industry Challenge. . | |
| 520 | |a This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pathological processing - have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up | ||
| 650 | 0 | |a Medicine & Public Health | |
| 650 | 0 | |a Medicine | |
| 650 | 0 | |a Medical laboratories | |
| 650 | 0 | |a Oncology | |
| 650 | 0 | |a Pathology | |
| 650 | 0 | |a Surgery | |
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