Applications of mass spectrometry imaging to cancer
Front Cover -- Applications of Mass Spectrometry Imaging to Cancer -- Copyright -- Contents -- Contributors -- Preface -- References -- Chapter One: The Importance of Histology and Pathology in Mass Spectrometry Imaging -- 1. Importance of Pathology -- 2. Possible Errors Caused by Tissue Inherent Fa...
Gespeichert in:
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| Dokumenttyp: | Book/Monograph |
| Sprache: | Englisch |
| Veröffentlicht: |
Cambridge
Academic Press
2017
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| Schriftenreihe: | Advances in cancer research
volume 134 |
| In: |
Advances in cancer research (volume 134)
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| Volumes / Articles: | Show Volumes / Articles. |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://ebookcentral.proquest.com/lib/kxp/detail.action?docID=4790273
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| Verfasserangaben: | edited by Richard R. Drake (Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, United States), Liam A. McDonnell (Leiden University Medical Center, Leiden, Netherlands, Fondazione Pisana per la Scienza ONLUS, Pisa, Italy) |
| Zusammenfassung: | Front Cover -- Applications of Mass Spectrometry Imaging to Cancer -- Copyright -- Contents -- Contributors -- Preface -- References -- Chapter One: The Importance of Histology and Pathology in Mass Spectrometry Imaging -- 1. Importance of Pathology -- 2. Possible Errors Caused by Tissue Inherent Factors-Why Histology Is Important for Supervised Analysis -- 3. Possible Errors Caused by Sample Inherent Factors-Small Pretherapeutic Biopsies -- 4. Possible Errors Caused by Sample Preparations-Artifacts Are Not Your Friend -- 5. Possible Errors Caused by Ill-Defined Sample Groups in the Training Set-Keep It Black and White/Shades of Gray Are Not ... -- 6. Conclusion -- References -- Chapter Two: Applications of Mass Spectrometry Imaging to Cancer -- 1. Introduction -- 1.1. The Advantages of MSI -- 1.2. The Basic Principles of MSI -- 1.2.1. MALDI-TOF -- 1.2.2. MALDI-FT-ICR -- 1.2.3. SIMS-TOF -- 1.2.4. DESI -- 2. Protein MSI in Cancer Research -- 2.1. Distinguishing Tissue Types by Peptide MSI -- 2.2. Determining Tumor Margins by Peptide MSI -- 2.3. Prediction of Metastasis by Peptide MSI -- 2.4. Analysing Chemoresponse by Peptide MSI -- 2.5. Identification of Diagnostic and Prognostic Markers by Peptide MSI -- 2.6. Characterisation of Intra- and Intertumor Variability by Peptide MSI -- 2.7. Practical Considerations for Proteolytic Peptide MSI: Sample Preparation -- 2.8. Practical Considerations for Peptide MSI: Spatial Resolution -- 2.9. Practical Considerations for Peptide MSI: Mass Analysers -- 2.10. Practical Considerations for Peptide MSI: Identification -- 3. Lipid MSI in Cancer Research -- 3.1. Profiling Lipids in Cancer by DESI-MSI -- 3.2. Profiling Lipids in Cancer by SIMS-MSI -- 4. Glycan MSI in Cancer Research -- 5. Drug Imaging in Cancer Research -- 5.1. MALDI-MSI on Tissue Sections -- 5.2. MALDI-MSI on Whole Body Sections. |
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| Beschreibung: | Online Resource |
| ISBN: | 9780128054406 |