Investigation of a new version of the liquid embolic agent PHIL with extra-low-viscosity in an endovascular embolization model
BACKGROUND AND PURPOSE: The type and composition of an embolic agent have a relevant influence on the performance of endovascular embolization. The aim of this study was to investigate a new version of the liquid embolic agent precipitating hydrophobic injectable liquid (PHIL) with extra-low-viscosi...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2018
|
| In: |
American journal of neuroradiology
Year: 2018, Volume: 39, Issue: 9, Pages: 1696-1702 |
| ISSN: | 1936-959X |
| DOI: | 10.3174/ajnr.A5750 |
| Online Access: | Verlag, Volltext: https://doi.org/10.3174/ajnr.A5750 Verlag, Volltext: http://www.ajnr.org/content/39/9/1696 
|
| Author Notes: | D.F. Vollherbst, R. Otto, M. Hantz, C. Ulfert, H.U. Kauczor, M. Bendszus, C.M. Sommer, M.A. Möhlenbruch |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1662496214 | ||
| 003 | DE-627 | ||
| 005 | 20220816122852.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190328s2018 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3174/ajnr.A5750 |2 doi | |
| 035 | |a (DE-627)1662496214 | ||
| 035 | |a (DE-599)KXP1662496214 | ||
| 035 | |a (OCoLC)1341205679 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Vollherbst, Dominik |d 1989- |e VerfasserIn |0 (DE-588)1071379569 |0 (DE-627)825819024 |0 (DE-576)407878866 |4 aut | |
| 245 | 1 | 0 | |a Investigation of a new version of the liquid embolic agent PHIL with extra-low-viscosity in an endovascular embolization model |c D.F. Vollherbst, R. Otto, M. Hantz, C. Ulfert, H.U. Kauczor, M. Bendszus, C.M. Sommer, M.A. Möhlenbruch |
| 264 | 1 | |c 2018 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 28.03.2019 | ||
| 520 | |a BACKGROUND AND PURPOSE: The type and composition of an embolic agent have a relevant influence on the performance of endovascular embolization. The aim of this study was to investigate a new version of the liquid embolic agent precipitating hydrophobic injectable liquid (PHIL) with extra-low-viscosity in an in vivo embolization model. - MATERIALS AND METHODS: Twenty-four embolization procedures were performed in the porcine rete mirabile. Eight embolizations were performed with PHIL 25% low viscosity, Squid 12, and standard PHIL 25%, respectively. Procedure time, required volume of embolic agent, visibility of the embolic agent, embolization control, embolization extent (ie, penetration of the rete mirabile), amount of reflux, and degree of embolization distal to the rete mirabile were assessed. - RESULTS: All embolic agents were adequately visible. The embolization extent was not significantly different among the 3 investigated agents; however, there was a tendency toward a higher embolization extent for PHIL 25% low viscosity (median embolization extent: 88% [PHIL 25% low viscosity]; 65% [Squid 12]; 60% [PHIL 25%]; P = .146). The amount of reflux was significantly lower for the extra-low-viscosity agents PHIL 25% low viscosity and Squid 12 compared with the standard PHIL 25% (median reflux distance: 8 mm [PHIL 25% low viscosity]; 6 mm [Squid 12]; 17 mm [PHIL 25%]; P = .011). All other embolization features did not differ among agents. - CONCLUSIONS: PHIL 25% low viscosity is a promising liquid embolic agent for endovascular embolization, featuring effective distal penetration, adequate visibility, a low amount of reflux, and good flow control. | ||
| 700 | 1 | |a Otto, Ruth |e VerfasserIn |0 (DE-588)1182045227 |0 (DE-627)1662536798 |4 aut | |
| 700 | 1 | |a Ulfert, Christian |e VerfasserIn |0 (DE-588)1160254486 |0 (DE-627)1023399040 |0 (DE-576)505801094 |4 aut | |
| 700 | 1 | |a Kauczor, Hans-Ulrich |d 1962- |e VerfasserIn |0 (DE-588)139267123 |0 (DE-627)70327113X |0 (DE-576)310955327 |4 aut | |
| 700 | 1 | |a Bendszus, Martin |e VerfasserIn |0 (DE-588)1032676426 |0 (DE-627)738634131 |0 (DE-576)175567697 |4 aut | |
| 700 | 1 | |a Sommer, Christof-Matthias |d 1978- |e VerfasserIn |0 (DE-588)133929701 |0 (DE-627)558738699 |0 (DE-576)278278035 |4 aut | |
| 700 | 1 | |a Möhlenbruch, Markus Alfred |d 1979- |e VerfasserIn |0 (DE-588)137693591 |0 (DE-627)594845041 |0 (DE-576)304845655 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t American journal of neuroradiology |d Oak Brook, Ill. : Soc., 1980 |g 39(2018), 9, Seite 1696-1702 |h Online-Ressource |w (DE-627)320647331 |w (DE-600)2025541-X |w (DE-576)101556217 |x 1936-959X |7 nnas |a Investigation of a new version of the liquid embolic agent PHIL with extra-low-viscosity in an endovascular embolization model |
| 773 | 1 | 8 | |g volume:39 |g year:2018 |g number:9 |g pages:1696-1702 |g extent:7 |a Investigation of a new version of the liquid embolic agent PHIL with extra-low-viscosity in an endovascular embolization model |
| 856 | 4 | 0 | |u https://doi.org/10.3174/ajnr.A5750 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u http://www.ajnr.org/content/39/9/1696 |x Verlag |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190328 | ||
| 993 | |a Article | ||
| 994 | |a 2018 | ||
| 998 | |g 137693591 |a Möhlenbruch, Markus Alfred |m 137693591:Möhlenbruch, Markus Alfred |d 910000 |d 911100 |e 910000PM137693591 |e 911100PM137693591 |k 0/910000/ |k 1/910000/911100/ |p 8 |y j | ||
| 998 | |g 133929701 |a Sommer, Christof-Matthias |m 133929701:Sommer, Christof-Matthias |d 910000 |d 911400 |e 910000PS133929701 |e 911400PS133929701 |k 0/910000/ |k 1/910000/911400/ |p 7 | ||
| 998 | |g 1032676426 |a Bendszus, Martin |m 1032676426:Bendszus, Martin |d 910000 |d 911100 |e 910000PB1032676426 |e 911100PB1032676426 |k 0/910000/ |k 1/910000/911100/ |p 6 | ||
| 998 | |g 139267123 |a Kauczor, Hans-Ulrich |m 139267123:Kauczor, Hans-Ulrich |d 910000 |d 911400 |e 910000PK139267123 |e 911400PK139267123 |k 0/910000/ |k 1/910000/911400/ |p 5 | ||
| 998 | |g 1160254486 |a Ulfert, Christian |m 1160254486:Ulfert, Christian |d 910000 |d 911100 |e 910000PU1160254486 |e 911100PU1160254486 |k 0/910000/ |k 1/910000/911100/ |p 4 | ||
| 998 | |g 1182045227 |a Otto, Ruth |m 1182045227:Otto, Ruth |d 910000 |d 911400 |e 910000PO1182045227 |e 911400PO1182045227 |k 0/910000/ |k 1/910000/911400/ |p 2 | ||
| 998 | |g 1071379569 |a Vollherbst, Dominik |m 1071379569:Vollherbst, Dominik |d 910000 |d 911100 |e 910000PV1071379569 |e 911100PV1071379569 |k 0/910000/ |k 1/910000/911100/ |p 1 |x j | ||
| 999 | |a KXP-PPN1662496214 |e 341725468X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["D.F. Vollherbst, R. Otto, M. Hantz, C. Ulfert, H.U. Kauczor, M. Bendszus, C.M. Sommer, M.A. Möhlenbruch"]},"note":["Gesehen am 28.03.2019"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"origin":[{"dateIssuedKey":"2018","dateIssuedDisp":"2018"}],"physDesc":[{"extent":"7 S."}],"relHost":[{"titleAlt":[{"title":"AJNR"}],"recId":"320647331","language":["eng"],"disp":"Investigation of a new version of the liquid embolic agent PHIL with extra-low-viscosity in an endovascular embolization modelAmerican journal of neuroradiology","id":{"zdb":["2025541-X"],"eki":["320647331"],"issn":["1936-959X"]},"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"dateIssuedDisp":"1980-","dateIssuedKey":"1980","publisherPlace":"Oak Brook, Ill.","publisher":"Soc."}],"type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 31.01.25","Fortsetzung der Druck-Ausgabe"],"pubHistory":["1.1980 -"],"part":{"volume":"39","year":"2018","text":"39(2018), 9, Seite 1696-1702","extent":"7","issue":"9","pages":"1696-1702"},"title":[{"title":"American journal of neuroradiology","subtitle":"AJNR","title_sort":"American journal of neuroradiology"}],"name":{"displayForm":["American Society of Neuroradiology"]}}],"title":[{"title":"Investigation of a new version of the liquid embolic agent PHIL with extra-low-viscosity in an endovascular embolization model","title_sort":"Investigation of a new version of the liquid embolic agent PHIL with extra-low-viscosity in an endovascular embolization model"}],"language":["eng"],"id":{"doi":["10.3174/ajnr.A5750"],"eki":["1662496214"]},"person":[{"roleDisplay":"VerfasserIn","given":"Dominik","display":"Vollherbst, Dominik","family":"Vollherbst","role":"aut"},{"role":"aut","family":"Otto","display":"Otto, Ruth","given":"Ruth","roleDisplay":"VerfasserIn"},{"display":"Ulfert, Christian","given":"Christian","roleDisplay":"VerfasserIn","role":"aut","family":"Ulfert"},{"family":"Kauczor","role":"aut","roleDisplay":"VerfasserIn","given":"Hans-Ulrich","display":"Kauczor, Hans-Ulrich"},{"family":"Bendszus","role":"aut","given":"Martin","roleDisplay":"VerfasserIn","display":"Bendszus, Martin"},{"given":"Christof-Matthias","roleDisplay":"VerfasserIn","display":"Sommer, Christof-Matthias","family":"Sommer","role":"aut"},{"display":"Möhlenbruch, Markus Alfred","given":"Markus Alfred","roleDisplay":"VerfasserIn","role":"aut","family":"Möhlenbruch"}],"recId":"1662496214"} | ||
| SRT | |a VOLLHERBSTINVESTIGAT2018 | ||