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Ibrutinib

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Abnormal B-cell receptor (BCR) signalling is a key mechanism of disease progression in B-cell malignancy. Bruton’s tyrosine kinase (BTK) has a pivotal role in BCR signalling. Ibrutinib (PCI-32765) is a small molecule which serves as a covalent irreversible inhibitor of BTK. It is characterized by hi...

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Main Authors: Charalambous, Andriani (Author) , Schwarzbich, Mark-Alexander (Author) , Witzens-Harig, Mathias (Author)
Format: Chapter/Article
Language:English
Published: [2018]
In: Small molecules in hematology
Year: 2018, Pages: 133-168
DOI:10.1007/978-3-319-91439-8_7
Online Access:Verlag, Volltext: https://doi.org/10.1007/978-3-319-91439-8_7
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Author Notes:Andriani Charalambous, Mark-Alexander Schwarzbich, Mathias Witzens-Harig
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Ibrutinib by Schwarzbich, Mark-Alexander (Author) , Witzens-Harig, Mathias (Author) ,


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