Hybridization and reaction-based fluorogenic nucleic acid probes
We developed fluorogenic probes, which are photoactivated in the presence of specific nucleic acid templates with the release of fluorescent dyes. This templated reaction can be used to target specific nucleic acids in complex mixtures. We further demonstrate that this reaction can be monitored by s...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2012
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| In: |
Chemical communications
Year: 2012, Volume: 48, Issue: 77, Pages: 9664-9666 |
| ISSN: | 1364-548X |
| DOI: | 10.1039/C2CC33827K |
| Online Access: | Verlag, Volltext: https://doi.org/10.1039/C2CC33827K Verlag, Volltext: https://pubs.rsc.org/en/content/articlelanding/2012/cc/c2cc33827k 
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| Author Notes: | Subrata Dutta, Benjamin Flottmann, Mike Heilemann and Andriy Mokhir |
| Summary: | We developed fluorogenic probes, which are photoactivated in the presence of specific nucleic acid templates with the release of fluorescent dyes. This templated reaction can be used to target specific nucleic acids in complex mixtures. We further demonstrate that this reaction can be monitored by single-molecule fluorescence imaging. |
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| Item Description: | Gesehen am 11.04.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1364-548X |
| DOI: | 10.1039/C2CC33827K |