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Facile synthesis of novel 3,4,5-trisubstituted-1,2,4-triazin-6(1H)-ones via a sequential Ugi-Smiles type/nucleophilic substitution/cyclization reaction

A simple and innovative strategy is described for synthesizing a library of novel 3,4,5-trisubstituted-1,2,4-triazin-6(1H)-one backbones in mild conditions. This approach involves multiple bond-forming events in an Ugi-Smiles type reaction and the post-condensation of the Ugi-Smiles adduct incorpora...

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Bibliographic Details
Main Authors: Ramezanpour, Sorour (Author) , Rominger, Frank (Author)
Format: Article (Journal)
Language:English
Published: 25 Sep 2018
In: New journal of chemistry
Year: 2018, Volume: 42, Issue: 21, Pages: 17533-17537
ISSN:1369-9261
DOI:10.1039/C8NJ03949F
Online Access:Verlag, Volltext: https://doi.org/10.1039/C8NJ03949F
Verlag, Volltext: https://pubs.rsc.org/en/content/articlelanding/2018/nj/c8nj03949f
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Author Notes:Sorour Ramezanpour, Mohammad Nasim Rezaei, Aref Vaezghaemi and Frank Rominger

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