CKAMP44 modulates integration of visual inputs in the lateral geniculate nucleus
The function of receptor desensitization in vivo is not well understood. Here, the authors show that deletion of CKAMP44, an AMPAR auxiliary protein that modulates desensitization of AMPAR currents, affects synaptic facilitation at retinogeniculate synapses and visually-evoked firing in awake mice.
Salvato in:
| Autori principali: | , |
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| Natura: | Article (Journal) |
| Lingua: | inglese |
| Pubblicazione: |
[2018]
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| In: |
Nature Communications
Year: 2018, Volume: 9 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-017-02415-1 |
| Accesso online: | Verlag, Volltext: https://doi.org/10.1038/s41467-017-02415-1 Verlag, Volltext: https://www.nature.com/articles/s41467-017-02415-1 
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| Note sull'autore: | Xufeng Chen, Muhammad Aslam, Tim Gollisch, Kevin Allen & Jakob von Engelhardt |
| Riassunto: | The function of receptor desensitization in vivo is not well understood. Here, the authors show that deletion of CKAMP44, an AMPAR auxiliary protein that modulates desensitization of AMPAR currents, affects synaptic facilitation at retinogeniculate synapses and visually-evoked firing in awake mice. |
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| Descrizione del documento: | Gesehen am 18.04.2019 |
| Descrizione fisica: | Online Resource |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-017-02415-1 |