Evidence of inflammasome activation and formation of monocyte-derived ASC specks in HIV-1 positive patients
Objective:The formation of large intracellular protein aggregates of the inflammasome adaptor protein ASC (apoptosis-associated speck-like protein containing a caspase-recruitment domain; also know as PYCARD) is a hallmark of inflammasome activation. ASC speck-forming cells release the highly proinf
Saved in:
| Main Author: | |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
January 28, 2018
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| In: |
AIDS <London>
Year: 2018, Volume: 32, Issue: 3, Pages: 299-307 |
| ISSN: | 1473-5571 |
| DOI: | 10.1097/QAD.0000000000001693 |
| Online Access: | Verlag, Volltext: https://journals.lww.com/aidsonline/Fulltext/2018/01280/Evidence_of_inflammasome_activation_and_formation.3.aspx Verlag, Volltext: https://doi.org/10.1097/QAD.0000000000001693 
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| Author Notes: | Fareed Ahmad, Neha Mishra, Gerrit Ahrenstorf, Bernardo Franklin, Eicke Latz, Reinhold Schmidt and Lukas Bossaller |
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