Evidence of inflammasome activation and formation of monocyte-derived ASC specks in HIV-1 positive patients
Objective:The formation of large intracellular protein aggregates of the inflammasome adaptor protein ASC (apoptosis-associated speck-like protein containing a caspase-recruitment domain; also know as PYCARD) is a hallmark of inflammasome activation. ASC speck-forming cells release the highly proinf
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
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January 28, 2018
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| In: |
AIDS <London>
Year: 2018, Jahrgang: 32, Heft: 3, Pages: 299-307 |
| ISSN: | 1473-5571 |
| DOI: | 10.1097/QAD.0000000000001693 |
| Online-Zugang: | Verlag, Volltext: https://journals.lww.com/aidsonline/Fulltext/2018/01280/Evidence_of_inflammasome_activation_and_formation.3.aspx Verlag, Volltext: https://doi.org/10.1097/QAD.0000000000001693 
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| Verfasserangaben: | Fareed Ahmad, Neha Mishra, Gerrit Ahrenstorf, Bernardo Franklin, Eicke Latz, Reinhold Schmidt and Lukas Bossaller |
| Zusammenfassung: | Objective:The formation of large intracellular protein aggregates of the inflammasome adaptor protein ASC (apoptosis-associated speck-like protein containing a caspase-recruitment domain; also know as PYCARD) is a hallmark of inflammasome activation. ASC speck-forming cells release the highly proinf |
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| Beschreibung: | Gesehen am 25.04.2019 DOI funktioniert nicht |
| Beschreibung: | Online Resource |
| ISSN: | 1473-5571 |
| DOI: | 10.1097/QAD.0000000000001693 |