Impact of carbonylation on glutathione peroxidase-1 activity in human hyperglycemic endothelial cells
Aims - High levels of glucose and reactive carbonyl intermediates of its degradation pathway such as methylglyoxal (MG) may contribute to diabetic complications partly via increased generation of reactive oxygen species (ROS). This study focused on glutathione peroxidase-1 (GPx1) expression and the...
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| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
01 March 2018
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| In: |
Redox Biology
Year: 2018, Jahrgang: 16, Pages: 113-122 |
| ISSN: | 2213-2317 |
| DOI: | 10.1016/j.redox.2018.02.018 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1016/j.redox.2018.02.018 Verlag, Volltext: http://www.sciencedirect.com/science/article/pii/S2213231718300533 |
| Verfasserangaben: | Cheryl S. Sultan, Andrea Saackel, Antonia Stank, Thomas Fleming, Maria Fedorova, Ralf Hoffmann, Rebecca C. Wade, Markus Hecker, Andreas H. Wagner |
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C332C genotype of glyoxalase 1 and its association with late diabetic complications: Glo1 genotype and diabetic neuropathy
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