Agnostic pathway/gene set analysis of genome-wide association data identifies associations for pancreatic cancer
Background: Genome-wide association studies (GWAS) identify associations of individual single-nucleotide polymorphisms (SNPs) with cancer risk but usually only explain a fraction of the inherited variability. Pathway analysis of genetic variants is a powerful tool to identify networks of susceptibil...
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| Main Authors: | , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
12 December 2018
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| In: |
Journal of the National Cancer Institute
Year: 2018, Volume: 111, Issue: 6, Pages: 1-11 |
| ISSN: | 1460-2105 |
| DOI: | 10.1093/jnci/djy155 |
| Online Access: | Verlag, Volltext: http://dx.doi.org/10.1093/jnci/djy155
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| Author Notes: | Naomi Walsh, Han Zhang, Paula L. Hyland, Qi Yang, Evelina Mocci, Mingfeng Zhang, Erica J. Childs, Irene Collins, Zhaoming Wang, Alan A. Arslan, Laura Beane-Freeman, Paige M. Bracci, Paul Brennan, Federico Canzian, Eric J. Duell, Steven Gallinger, Graham G. Giles, Michael Goggins, Gary E. Goodman, Phyllis J. Goodman, Rayjean J. Hung, Charles Kooperberg, Robert C. Kurtz, Núria Malats, Loic LeMarchand, Rachel E. Neale, Sara H. Olson, Ghislaine Scelo, Xiao O. Shu, Stephen K. Van Den Eeden, Kala Visvanathan, Emily White, Wei Zheng, PanScan and PanC4 consortia, Demetrius Albanes, Gabriella Andreotti, Ana Babic, William R. Bamlet, Sonja I. Berndt, Ayelet Borgida, Marie-Christine Boutron-Ruault, Lauren Brais, Paul Brennan, Bas Bueno-de-Mesquita, Julie Buring, Kari G. Chaffee, Stephen Chanock, Sean Cleary, Michelle Cotterchio, Lenka Foretova, Charles Fuchs, J. Michael M Gaziano, Edward Giovannucci, Michael Goggins, Thilo Hackert, Christopher Haiman, Patricia Hartge, Manal Hasan, Kathy J. Helzlsouer, Joseph Herman, Ivana Holcatova, Elizabeth A. Holly, Robert Hoover, Rayjean J. Hung, Vladimir Janout, Eric A. Klein, Robert C. Kurtz, Daniel Laheru, I.-Min Lee, Lingeng Lu, Núria Malats, Satu Mannisto, Roger L. Milne, Ann L. Oberg, Irene Orlow, Alpa V. Patel, Ulrike Peters, Miquel Porta, Francisco X. Real, Nathaniel Rothman, Howard D. Sesso, Gianluca Severi, Debra Silverman, Oliver Strobel, Malin Sund, Mark D. Thornquist, Geoffrey S. Tobias, Jean Wactawski-Wende, Nick Wareham, Elisabete Weiderpass, Nicolas Wentzensen, William Wheeler, Herbert Yu, Anne Zeleniuch-Jacquotte, Peter Kraft, Donghui Li, Eric J. Jacobs, Gloria M. Petersen, Brian M. Wolpin, Harvey A. Risch, Laufey T. Amundadottir, Kai Yu, Alison P. Klein, Rachael Z. Stolzenberg-Solomon |
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