Silver-catalyzed carboxylative cyclization of primary propargyl alcohols with CO2
By using silver complexes with bulky ligands such as DavePhos or N-heterocyclic carbenes, propargylic alcohols are smoothly converted with CO2 into a unique class of unexplored cyclic alkylidene carbonates. These systems, for the first time, also achieve the direct carboxylative cyclization of prima...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
February 20, 2019
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| In: |
Organic letters
Year: 2019, Volume: 21, Issue: 5, Pages: 1422-1425 |
| ISSN: | 1523-7052 |
| DOI: | 10.1021/acs.orglett.9b00156 |
| Online Access: | Verlag, Volltext: https://doi.org/10.1021/acs.orglett.9b00156
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| Author Notes: | Saumya Dabral, Bilguun Bayarmagnai, Marko Hermsen, Jasmin Schießl, Verena Mormul, A. Stephen K. Hashmi, and Thomas Schaub |
| Summary: | By using silver complexes with bulky ligands such as DavePhos or N-heterocyclic carbenes, propargylic alcohols are smoothly converted with CO2 into a unique class of unexplored cyclic alkylidene carbonates. These systems, for the first time, also achieve the direct carboxylative cyclization of primary propargylic alcohols. The silver-DavePhos catalyst is further applied for the bis-carboxylative cyclization of primary propargyl derivatives, thereby providing an effective route to a series of previously inaccessible and industrially relevant α-alkylidene cyclic carbonates. |
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| Item Description: | Im Titel ist „2“ tiefgestellt Gesehen am 09.05.2019 |
| Physical Description: | Online Resource |
| ISSN: | 1523-7052 |
| DOI: | 10.1021/acs.orglett.9b00156 |