Acute canagliflozin treatment protects against in vivo myocardial ischemia–reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation
The sodium–glucose cotransporter-2 (SGLT2) inhibitor canagliflozin has been shown to reduce major cardiovascular events in type 2 diabetic patients, with a pronounced decrease in hospitalization for heart failure (HF) especially in those with HF at baseline. These might indicate a potent direct card...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
16 April 2019
|
| In: |
Journal of translational medicine
Year: 2019, Jahrgang: 17, Pages: 1-14 |
| ISSN: | 1479-5876 |
| DOI: | 10.1186/s12967-019-1881-8 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1186/s12967-019-1881-8
|
| Verfasserangaben: | Alex Ali Sayour, Sevil Korkmaz-Icöz, Sivakkanan Loganathan, Mihály Ruppert, Viktor Nabil Sayour, Attila Oláh, Kálmán Benke, Maik Brune, Rita Benkő, Eszter Mária Horváth, Matthias Karck, Béla Merkely, Tamás Radovits and Gábor Szabó |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1665337176 | ||
| 003 | DE-627 | ||
| 005 | 20230427000813.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 190514s2019 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1186/s12967-019-1881-8 |2 doi | |
| 035 | |a (DE-627)1665337176 | ||
| 035 | |a (DE-599)KXP1665337176 | ||
| 035 | |a (OCoLC)1341213094 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Sayour, Alex Ali |d 1994- |e VerfasserIn |0 (DE-588)1186074191 |0 (DE-627)1665335416 |4 aut | |
| 245 | 1 | 0 | |a Acute canagliflozin treatment protects against in vivo myocardial ischemia–reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation |c Alex Ali Sayour, Sevil Korkmaz-Icöz, Sivakkanan Loganathan, Mihály Ruppert, Viktor Nabil Sayour, Attila Oláh, Kálmán Benke, Maik Brune, Rita Benkő, Eszter Mária Horváth, Matthias Karck, Béla Merkely, Tamás Radovits and Gábor Szabó |
| 264 | 1 | |c 16 April 2019 | |
| 300 | |a 14 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 14.05.2019 | ||
| 520 | |a The sodium–glucose cotransporter-2 (SGLT2) inhibitor canagliflozin has been shown to reduce major cardiovascular events in type 2 diabetic patients, with a pronounced decrease in hospitalization for heart failure (HF) especially in those with HF at baseline. These might indicate a potent direct cardioprotective effect, which is currently incompletely understood. We sought to characterize the cardiovascular effects of acute canagliflozin treatment in healthy and infarcted rat hearts. | ||
| 700 | 1 | |a Korkmaz-İçöz, Sevil |e VerfasserIn |0 (DE-588)1062748697 |0 (DE-627)806830336 |0 (DE-576)420147845 |4 aut | |
| 700 | 1 | |a Loganathan, Sivakkanan |d 1984- |e VerfasserIn |0 (DE-588)1036717585 |0 (DE-627)75102550X |0 (DE-576)385350856 |4 aut | |
| 700 | 1 | |a Ruppert, Mihály |d 1990- |e VerfasserIn |0 (DE-588)110439846X |0 (DE-627)861860586 |0 (DE-576)470970464 |4 aut | |
| 700 | 1 | |a Brune, Maik |d 1974- |e VerfasserIn |0 (DE-588)130611883 |0 (DE-627)504641948 |0 (DE-576)298297930 |4 aut | |
| 700 | 1 | |a Karck, Matthias |d 1961- |e VerfasserIn |0 (DE-588)130833525 |0 (DE-627)505909340 |0 (DE-576)298366169 |4 aut | |
| 700 | 1 | |a Szabó, Gábor |d 1969- |e VerfasserIn |0 (DE-588)1022955152 |0 (DE-627)717338681 |0 (DE-576)366215485 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of translational medicine |d London : BioMed Central, 2003 |g 17(2019), Artikel-ID 127, Seite 1-14 |h Online-Ressource |w (DE-627)369084136 |w (DE-600)2118570-0 |w (DE-576)107015994 |x 1479-5876 |7 nnas |a Acute canagliflozin treatment protects against in vivo myocardial ischemia–reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation |
| 773 | 1 | 8 | |g volume:17 |g year:2019 |g elocationid:127 |g pages:1-14 |g extent:14 |a Acute canagliflozin treatment protects against in vivo myocardial ischemia–reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation |
| 856 | 4 | 0 | |u https://doi.org/10.1186/s12967-019-1881-8 |x Verlag |x Resolving-System |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20190514 | ||
| 993 | |a Article | ||
| 994 | |a 2019 | ||
| 998 | |g 1022955152 |a Szabó, Gábor |m 1022955152:Szabó, Gábor |d 910000 |d 910200 |e 910000PS1022955152 |e 910200PS1022955152 |k 0/910000/ |k 1/910000/910200/ |p 14 |y j | ||
| 998 | |g 130833525 |a Karck, Matthias |m 130833525:Karck, Matthias |d 910000 |d 910200 |e 910000PK130833525 |e 910200PK130833525 |k 0/910000/ |k 1/910000/910200/ |p 11 | ||
| 998 | |g 130611883 |a Brune, Maik |m 130611883:Brune, Maik |d 910000 |d 910100 |e 910000PB130611883 |e 910100PB130611883 |k 0/910000/ |k 1/910000/910100/ |p 8 | ||
| 998 | |g 110439846X |a Ruppert, Mihály |m 110439846X:Ruppert, Mihály |p 4 | ||
| 998 | |g 1036717585 |a Loganathan, Sivakkanan |m 1036717585:Loganathan, Sivakkanan |d 50000 |e 50000PL1036717585 |k 0/50000/ |p 3 | ||
| 998 | |g 1062748697 |a Korkmaz-İçöz, Sevil |m 1062748697:Korkmaz-İçöz, Sevil |d 910000 |d 910200 |e 910000PK1062748697 |e 910200PK1062748697 |k 0/910000/ |k 1/910000/910200/ |p 2 | ||
| 998 | |g 1186074191 |a Sayour, Alex Ali |m 1186074191:Sayour, Alex Ali |d 910000 |d 910200 |e 910000PS1186074191 |e 910200PS1186074191 |k 0/910000/ |k 1/910000/910200/ |p 1 |x j | ||
| 999 | |a KXP-PPN1665337176 |e 3475649713 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"origin":[{"dateIssuedKey":"2019","dateIssuedDisp":"16 April 2019"}],"note":["Gesehen am 14.05.2019"],"recId":"1665337176","language":["eng"],"name":{"displayForm":["Alex Ali Sayour, Sevil Korkmaz-Icöz, Sivakkanan Loganathan, Mihály Ruppert, Viktor Nabil Sayour, Attila Oláh, Kálmán Benke, Maik Brune, Rita Benkő, Eszter Mária Horváth, Matthias Karck, Béla Merkely, Tamás Radovits and Gábor Szabó"]},"person":[{"family":"Sayour","display":"Sayour, Alex Ali","role":"aut","given":"Alex Ali"},{"display":"Korkmaz-İçöz, Sevil","family":"Korkmaz-İçöz","given":"Sevil","role":"aut"},{"family":"Loganathan","display":"Loganathan, Sivakkanan","role":"aut","given":"Sivakkanan"},{"role":"aut","given":"Mihály","family":"Ruppert","display":"Ruppert, Mihály"},{"role":"aut","given":"Maik","family":"Brune","display":"Brune, Maik"},{"display":"Karck, Matthias","family":"Karck","given":"Matthias","role":"aut"},{"given":"Gábor","role":"aut","display":"Szabó, Gábor","family":"Szabó"}],"title":[{"title_sort":"Acute canagliflozin treatment protects against in vivo myocardial ischemia–reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation","title":"Acute canagliflozin treatment protects against in vivo myocardial ischemia–reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxation"}],"relHost":[{"disp":"Acute canagliflozin treatment protects against in vivo myocardial ischemia–reperfusion injury in non-diabetic male rats and enhances endothelium-dependent vasorelaxationJournal of translational medicine","origin":[{"publisherPlace":"London","dateIssuedKey":"2003","publisher":"BioMed Central","dateIssuedDisp":"2003-"}],"part":{"text":"17(2019), Artikel-ID 127, Seite 1-14","volume":"17","year":"2019","extent":"14","pages":"1-14"},"recId":"369084136","note":["Gesehen am 22.06.20"],"language":["eng"],"title":[{"title":"Journal of translational medicine","title_sort":"Journal of translational medicine"}],"physDesc":[{"extent":"Online-Ressource"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"id":{"zdb":["2118570-0"],"issn":["1479-5876"],"eki":["369084136"]},"pubHistory":["1.2003 -"]}],"physDesc":[{"extent":"14 S."}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"id":{"eki":["1665337176"],"doi":["10.1186/s12967-019-1881-8"]}} | ||
| SRT | |a SAYOURALEXACUTECANAG1620 | ||